首页> 外文期刊>Journal of Medical Physics/Association of Medical Physicists of India >A method to improve fluence resolution derived from two-dimensional detector array measurements for patient-specific IMRT verification using the information collected in dynalog files
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A method to improve fluence resolution derived from two-dimensional detector array measurements for patient-specific IMRT verification using the information collected in dynalog files

机译:一种使用二维文件中收集的信息来提高针对二维二维检测器阵列测量的注量分辨率的方法,以进行针对患者的IMRT验证

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This paper proposes a method for improving the resolution of the fluence derived from detector array measurement using the information collected in dynalog files. From dynalog information, a file is generated with the actual multileaf collimator (MLC) positions and used as input to the treatment planning system (TPS) to obtain the dynalog-derived fluence and the theoretical response over the detector array. In contrast with the measured response, this theoretical response allows for correction of the dynalog-derived fluence and translation into the reconstructed fluence. This fluence is again introduced into the planning system to verify the treatment using clinical tools. Initially, more than 98% of the points passed the two-dimensional (2D) phantom gamma test (3% local dose - 3 mm) for all of the treatment verifications, but in some dose–volume histogram (DVH) comparisons, we note sensitive differences for the planning target volume (PTV) coverage and for the maximum doses in at-risk organs (up to 3.5%). In dose–distribution evaluations, we found differences of up to 5% in the PTV edges in certain cases due to detector array measurement errors. This work improves the resolution of the fluence derived from detector array measurements based on the treatment information, in contrast with the current commercial proposals based on planned data.Keywords: Dynalog, 2D array, fluence, intensity-modulated radiotherapy, three-dimensional verification
机译:本文提出了一种方法,该方法利用在动态文件中收集的信息来提高从探测器阵列测量中得出的注量的分辨率。根据动态信息,将使用实际的多叶准直仪(MLC)位置生成文件,并将其用作治疗计划系统(TPS)的输入,以获取基于动态信息的通量和探测器阵列上的理论响应。与测得的响应相反,该理论响应允许对源自动态的注量进行校正并转化为重构注量。该通量再次被引入计划系统以使用临床工具来验证治疗。最初,对于所有治疗验证,超过98%的点都通过了二维(2D)幻像伽玛测试(3%局部剂量-3 mm),但是在某些剂量-体积直方图(DVH)比较中,我们注意到计划目标量(PTV)覆盖范围和高风险器官中的最大剂量(最高3.5%)之间存在敏感差异。在剂量分布评估中,由于检测器阵列测量误差,在某些情况下,我们发现PTV边缘的差异高达5%。与目前基于计划数据的商业提案相比,这项工作提高了根据治疗信息从检测器阵列测量获得的注量的分辨率。关键词:Dynalog,2D阵列,注量,强度调制放射疗法,三维验证

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