Comparison of Demographic, Clinical, Radiological Characteristics and Comorbidities in Mechanically Ventilated and Nonventilated, Adult Patients Admitted in ICU with Confirmed Diagnosis of Influenza A (H1N1)

摘要

Introduction : Influenza A(H1N1) infection affected Indian population in 2009. Patients needed ICU admission and monitoring. Simple demographic, clinical and radiological variables are described in this article in mechanically ventilated and nonventilated patients.Objectives : To describe and correlate demographic, clinical, radiographic characteristics and comorbidities in mechanically ventilated and nonventilated, adult patients admitted in ICU with confirmed diagnosis of Influenza A(H1N1) infection.Material and methods : Retrospective study of records of 100 RT-PCR confirmed patients with Influenza A (H1N1) infection from August 2009 to March 2010 was done. Each patient underwent an evaluation to determine demographic, clinical and radiographic features, comorbidities, mechanical ventilator required or notResults : 35 Patients required mechanical ventilation. 27 required IMV, 4 required NIMV while 4 patients initially were put on NIMV required IMV subsequently. 19 (40.42%) female patients required mechanical ventilator. Mean age of mechanically ventilated patients was 33 years, mean duration of illness was 7.9 days, mean duration of hospital stay was 6.8 days. 07(20.00%) patients with pregnancy, 05 (14.29%) with DM, 05 (14.29%) with HT, 04/11.43%) with obesity required mechanical ventilator. 97.14% patients with fever, 88.54% with breathlessness, 11.43% with haemoptysis, 31.42% patients with throat pain required mechanical ventilator. However except Tachypnoea (p Conclusions : Mechanical ventilation requirement was more in females, in presence of comorbidities like pregnancy, DM, HT, in presence of tachypnoea, in presence of bilateral disease and in presence of middle zone and right upper zone disease and with multiple zone disease. All patients with heart involvement required mechanical ventilator. If there is radiological finding of right upper zone involvement, then, there is more probability that these patients require mechanical ventilator for case management. Similarly, RMZ, LMZ and RLZ and cardiomegaly if shown in X-ray, the necessity of ventilator management is more