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Pancreatic Schwannoma: A Case Report and Literature Review with Special Reference to Imaging Features

机译:胰腺神经鞘瘤:病例报告和文献复习,特别涉及影像学特征

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Context We report theimaging features of pancreatic schwannomas, a rare benign type of pancreatictumor. Case report A 66-year-old woman was admitted to our hospital witha pancreatic tumor indicated in medical examinations. Computed tomography (CT),magnetic resonance imaging (MRI) and endoscopic ultrasonography (EUS) revealeda solid and cystic tumor, 3 cm in diameter, within the body of the pancreas.Contrast-enhanced CT, MRI and ultrasonography showed partial enhancement in thesolid component. Endoscopic retrograde cholangiopancreatography (ERCP) andangiography showed no abnormal findings. A distal pancreatectomy together witha splenectomy and lymph node dissection were performed with a tentativediagnosis of mucinous cystic neoplasm of the pancreas. The cut surface of theresected pancreas showed a well-demarcated, pale yellow, solid tumor within thepancreas parenchyma. Histopathological examination of the tumor revealedproliferation of the spindle cells showing interlacing and palisading patterns.Immunohistochemically, these spindle cells were positive for S-100 protein andvimentin, and negative for alpha-smooth muscle actin, CD34, and cytokeratin.Thus the tumor was diagnosed as a pancreatic schwannoma. Conclusion CTand US can detect pancreatic schwannomas as solid and cystic masses, and MRIshows a relatively characteristic feature. Imaging procedures such as CT, MRIand US are able to differentiate a pancreatic tumor, such as a pancreaticschwannoma.
机译:背景我们报道了胰腺神经鞘瘤(一种罕见的良性胰腺肿瘤)的影像学特征。病例报告一名66岁的女性因体检发现胰腺肿瘤入院。计算机断层扫描(CT),磁共振成像(MRI)和内窥镜超声检查(EUS)显示胰腺体内存在直径为3 cm的实体和囊性肿瘤,而增强CT,MRI和超声检查显示固体成分部分增强。内镜逆行胰胆管造影(ERCP)和血管造影未见异常发现。进行胰腺远端切除术,脾切除术和淋巴结清扫术,初步诊断胰腺粘液性囊性肿瘤。切除的胰腺的切面显示出在胰腺实质内的界限清楚的浅黄色实体瘤。肿瘤的组织病理学检查显示纺锤体细胞增生,呈交错和弥散模式。免疫组织化学检查,这些纺锤体细胞对S-100蛋白和波形蛋白呈阳性,而对α平滑肌肌动蛋白,CD34和细胞角蛋白呈阴性,因此被诊断为胰腺神经鞘瘤。结论CT和US能检出胰腺神经管瘤的实性和囊性肿块,MRI具有相对特征性。诸如CT,MRI和US的成像程序能够区分胰腺肿瘤,例如胰腺神经鞘瘤。

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