Symmetrical peripheral gangrene and scrotal gangrene in a falciparum malaria case

摘要

Peripheral gangrene, characterised by distal ischaemia of the extremities, is a rare complication in patients with falciparum malaria.Though many case reports have been published regarding association of peripheral gangrene and falciparum malaria, in thisreport, we describe a 40-year-old male who presented with high-grade fever for 6 - 9 days, jaundice, and gangrene which developedat all four limbs; and besides this he also developed scrotal gangrene. Blood smears revealed hyperparasitaemia with Plasmodiumfalciparum. The most common pathophysiology is disseminated intravascular coagulation (DIC) secondary to malaria infection,although other mechanisms are also involved. In our case there was no any evidence of sepsis, disseminated intravascularcoagulation, Raynaud's phenomenon