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首页> 外文期刊>Journal of Thoracic Disease >A predictor for mitral valve repair in patient with rheumatic heart disease: the bending angle of anterior mitral leaflet
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A predictor for mitral valve repair in patient with rheumatic heart disease: the bending angle of anterior mitral leaflet

机译:风湿性心脏病患者二尖瓣修复的预测指标:二尖瓣前叶的弯曲角度

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Background: Mobility and flexibility of anterior mitral leaflet (AML) are considered to be the important factor for mitral valve (MV) repair in rheumatic population, we try to use the bending angle of AML to quantify its’ mobility and flexibility and investigate whether it can predict the success of rheumatic MV repair or not. Methods: Total 54 patients underwent rheumatic MV surgeries with mild lesions of subvalvular apparatus from August, 2017 to November, 2017 at the author institution, we divided the patients into MV repair and MV replacement groups which included directly MV replacement and repair attempt but failed repairing transfer to replacement intraoperatively. Patients’ MV structure was carefully evaluated on transthoracic echocardiography (TTE) and scored by the Wilkins score (WS) preoperatively. The bending angle of AML was measured during systole and diastole at different level before surgery. Results: The differences of patients’ demographic characteristics between repair group and replacement group were not statistically significant (P value 0.05) and the differences among B-angle, T-angle, Bs-angle, C-angle of AML between repair group and replacement groups were not statistically significant (P value 0.05). Only BT-angle in repair group was significantly larger than that of replacement group (21.56°±3.84°, 10.29°±6.02°, respectively, P 0.05, the minor single calcified area at commissure had no effect on reparability of rheumatic MV disease. The differences of total WS and each component score between repair group and replacement group were not statistically significant (P value 0.05). By observing the ROC curve for total WS (ROC area: 0.508), the WS cannot be a predictor for the rheumatic MV repair. Conclusions: The bending angle of AML which was considered as quantification of mobility and flexibility of AML can be a predictor for MV repair in patients with rheumatic heart disease (RHD). The small single area of commissural calcification had no effect on reparability of rheumatic MV disease. WS cannot appropriately predict the outcome of rheumatic MV repair.
机译:背景:二尖瓣前叶(AML)的活动性和柔韧性被认为是风湿性人群二尖瓣(MV)修复的重要因素,我们尝试使用AML的弯曲角度来量化其活动性和柔韧性,并研究是否可以预测风湿性MV修复的成功与否。方法:自2017年8月至2017年11月在作者机构对54例行风湿性MV瓣膜下病变轻度手术的患者进行分类,将其分为MV修复组和MV替代组,包括直接MV替代和修复尝试但修复失败的患者术中转移至置换。术前对患者的MV结构进行了仔细的经胸超声心动图(TTE)评估,并通过Wilkins评分(WS)进行评分。术前分别在不同水平的收缩期和舒张期测量AML的弯曲角度。结果:修复组与置换组患者的人口统计学差异无统计学意义(P值> 0.05),修复组与替代组的AML的B角,T角,Bs角,C角之间差异无统计学意义。替代组无统计学意义(P值> 0.05)。修复组仅BT角显着大于置换组(分别为21.56°±3.84°,10.29°±6.02°,P <0.05),合缝处较小的单个钙化区域对风湿性MV疾病的可修复性没有影响。修复组和置换组的总WS和各成分评分的差异无统计学意义(P值> 0.05),通过观察总WS的ROC曲线(ROC面积:0.508),WS不能作为风湿病的预测指标MV修复结论:AML的弯曲角度被认为是AML的活动性和柔韧性的量化指标,可以预测风湿性心脏病(RHD)患者的MV修复,连合钙化的小面积对可修复性没有影响WS无法正确预测风湿性MV修复的结果。

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