Normal clinical electroretinography parameters for poodle,?Labrador retriever, Thai ridgeback, and Thai Bangkaew

摘要

The purpose of the present study was to establish normal electroretinogram (ERG) parameters using 56 normal eyes of four dog breeds common?in Thailand: poodle, Labrador retriever, Thai ridgeback, and Thai Bangkaew. Standard ERG findings were bilaterally recorded using a?handheld multi-species ERG unit with an ERG-jet lens electrode for 28 dogs under preanesthesia with diazepam, anesthesia with propofol,?and anesthesia maintenance with isoflurane. There were significant differences in the mean values of ERG amplitudes and implicit times?among the four dog breeds (p＜ 0.05) except for the b-wave implicit time of the photopic 30 Hz flicker response with 3 cd.s/m2 (p?= 0.610).?Out of the four breeds, Thai Bangkaew had the longest implicit time (p?＜ 0.001) of scotopic low intensity responses, b-wave of scotopic?standard intensity responses (3 cd.s/m2 ), a-wave of the higher intensity response (10 cd.s/m2 ), and a-wave of the photopic single flash response?(3 cd.s/m2 ). For the b/a ratio, only the ratio of the Cone response was significantly different among the different breeds. In this summary, normal?ERG parameters for four dog breeds were reported. Data from the investigation supported the hypothesis that determination of breed-specific?limits of normality for ERG responses is necessary for individual clinics and laboratories.