Effects of Exercise Training on Acute Myocardial Infarction Patients with Type 2 Diabetes: Comparison of Exercise Versus No Exercise in the Outpatient Recovery Period

摘要

Objective : The present retrospective study aimed to clarify the involvement of knee extensor strength and autonomic indices （ Δ HR) in the improvement of exercise capacity (peak VO₂) in acute myocardial infarction (AMI) patients with type 2 diabetes mellitus (DM) undergoing cardiac rehabilitation (CR) -related exercise training. Methods : A total of 41 consecutive male AMI patients with type 2 DM were divided into the supervised outpatient CR group (n = 24) and the non-CR group (control, n = 17). Physical training was prescribed for 8 weeks in the CR group. Cardiopulmonary exercise testing (peak VO₂, Δ HR) and isokinetic knee extension strength measurements were performed on all subjects at 1 (T1) and 3 (T2) months after AMI onset. Results : Significantly greater improvements in peak VO₂ (26.1→29.4 vs 23.5→24.4 ml/kg/min, F = 7.5， p ＜0.01), knee extension strength (1.7 →1.9 vs 1.7 →1.7 Nm/kg，F=5.1，p = 0.02), and Δ HR (71.3 →77.2 vs 63.5 →62.5 bpm, F = 5.5, p = 0.02) were measured from T1 to T2 in the CR group versus the nonCR group. Conclusions : In patients with AMI complicated by DM, only the exercise group showed significant improvements in knee extensor strength and Δ HR. Therefore, improvement in exercise capacity in such patients was considered to be related to improvements in knee extensor strength and Δ HR.