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Review of Tami I. Spector’s “From the Molecular to the Machine”

机译:评论Tami I. Spector的“从分子到机器”

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Objectivity can be a shady matter. More so when it supposedly arises from the "shadow images" portrayed by nanoscopy. Starting from a specific molecule, benzene, and the story of its discovery, Tami Spector builds an account that entwines the micro-world of nanomolecular studies with more general philosophical concerns for the representation of non-visible objects: "We had seen the unknowable. Or had we. Can we." (1). Problems with negotiation of meaning between the object and its structure are the underlying leitmotivs of a story that spans from Friedrich August Kekulé's epiphanic discovery of benzene's structure in 1865, to the 2001 STM (Scanning Tunneling Microscope) image of C60 (buckministerfullerene). Spector's article begins by presenting Kekulé's depiction of benzene as an historical marker for molecular representations. She argues that Kekule's idea of portraying benzene's cyclic valence structure in the form of an "uroboros," transformed a chemical formula into an enduring symbol and into a powerful signifier "where structure begets properties and properties recapitulate structure" (3). Images of molecules, like Platonic solids, which synthesise the quintessence of the objects from the tangible world, are but "imperfect simulacra" (5) of a reality that escapes our senses. Spector claims that, very much like those solids, such representations can operate on a metaphorical level stimulating productive connections and generating new understanding. It is within this framework that she presents the case of buckministerfullerene ("buckyball" for brevity), a "carbon-based polyhedral structure" (5) imbued with a "primal Platonic essence" (9). According to Spector, however, the resemblance of this molecule with an everyday object such as a soccer ball, gives it an adjunct value in respect to Platonic solids. Its ball-like nature reflects its function in real life as a potential vehicle for delivering drugs to a specific target in the body: "not only does it look like a real-world object; it theoretically acts like one too" (9). For Spector, Buckyball also marks the passage from molecules to more complex switch-like functioning systems called molecular machines: organised aggregates of molecular components that produce kinetic responses to specific stimuli, mimicking their macroscopic homonyms. These idealised mini-machines represent one part of that "machine" mentioned in the title of Spector's article, the other part being the actual machines, such as the STM or the SPM (Scanning Probe Microscope), used to detect them. The symbolical union of the object of study and the recording device, registered in the title under one single all-encompassing word, hints at Spector's main argument that the real substance of nanotechnology consists of nanomicroscopy images rather than the actual nanoscale objects (17).
机译:客观性可能是一个阴暗的问题。当它据推测是由纳米显微镜描绘的“阴影图像”时更是如此。从一个特定的分子,苯及其发现的故事开始,Tami Spector建立了一个账户,该账户将纳米分子研究的微观世界与对不可见物体的表示的更一般的哲学关注联系在一起:“我们已经看到了不可知的东西。还是我们。我们可以。” (1)。物体与其结构之间的意义协商存在的问题是该故事的潜在主旨,其范围从1865年弗里德里希·奥古斯特·库库莱(Friedrich AugustKekulé)突然发现苯的结构,到2001年STM(扫描隧道显微镜)C60(buckministerfullerene)图像。 Spector的文章首先介绍了Kekulé对苯作为分子表征历史标记的描述。她认为,Kekule以“ uroboros”的形式描绘苯的环价结构的想法,将化学式转变为持久的符号,并转变为强有力的指示符,“其中的结构引发了性质,而性质又概括了结构”(3)。分子(例如柏拉图式固体)的图像合成了有形世界中物体的精髓,但这只是逃避我们感官的现实的“不完美的模仿”(5)。 Spector声称,与这些实体非常相似,此类表示形式可以在隐喻级别进行操作,从而激发生产联系并产生新的理解。在此框架内,她介绍了buckministerfullerene(为简便起见,为“ buckyball”)案例,这是一种“基于碳的多面体结构”(5),其中充满了“原始柏拉图本质”(9)。但是,据Spector认为,该分子与日常物体(如足球)的相似性使其相对于柏拉图固体具有附加值。它的球形性质反映了它在现实生活中的功能,将其作为将药物输送到体内特定目标的潜在媒介:“它不仅看起来像真实世界的物体,而且在理论上也像一个物体”(9)。对于Spector来说,Buckyball还标志着从分子到更复杂的类似开关的功能系统(称为分子机器)的转变:分子组件的有组织的聚集体,产生对特定刺激的动力学响应,模仿其宏观同源性。这些理想化的微型机器代表了Spector文章标题中提到的“机器”的一部分,另一部分是用于检测它们的实际机器,例如STM或SPM(扫描探针显微镜)。研究对象和记录设备的象征性结合,在标题中以一个单一的,包含所有含义的词表示,暗示了Spector的主要论点是,纳米技术的真正实质是由纳米显微镜图像而不是实际的纳米级对象构成(17)。

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