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A clinical study on oral lichen planus with special emphasis on hyperpigmentation

机译:口腔扁平苔藓特别是色素沉着过度的临床研究

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Background:Oral lichen planus (OLP) is a unique disorder affecting generally the older age group. Numerous studies have been done on various aspects of OLP such as pathogenesis, rate of malignant transformation, etc. However, very few studies are available with respect to clinical features especially association of hyperpigmentation and OLP. This study aims at studying the clinical aspects of OLP and study the association between hyperpigmentation and OLP in a south Indian population.Materials and Methods:A total of 58 patients with OLP who attended the outpatient department of our institution were included in the study and a complete history, followed by thorough intraoral examination was done. All the data were recorded and assessed for statistical analysis using SPSS software.Results:We found that the male to female ratio affected with OLP was 1:1 and the most common form of OLP that was seen was the reticular subtype. Also, buccal mucosa was the most common affected site and more than 60% patients had hyperpigmentation associated with the site affected by OLP. We found a statistically significant relation between the reticular type of OLP and the older age group (51–70 years) with hyperpigmentation.Conclusion:Although further studies are required to say anything conclusively, post-inflammatory changes occurring the mucosa due to OLP could be a cause for hyperpigmentation in the sites affected.
机译:背景:口腔扁平苔藓(OLP)是一种普遍影响老年人群的独特疾病。已经对OLP的各个方面进行了许多研究,例如发病机理,恶性转化率等。但是,关于临床特征,尤其是色素沉着过度与OLP的关联,仅有很少的研究。这项研究旨在研究印度南部人口中OLP的临床情况,并研究色素沉着与OLP的相关性。材料与方法:本研究共纳入58例本院门诊就诊的OLP患者。病史完整,随后进行彻底的口内检查。结果:我们发现受OLP影响的男女比例为1:1,而最常见的OLP形式是网状亚型。而且,颊粘膜是最常见的受累部位,超过60%的患者有与受OLP影响的部位相关的色素沉着过度。我们发现网状OLP类型与色素沉着过度的老年组(51-70岁)之间存在统计学上的显着关系。结论:尽管需要进一步的研究来得出结论性结论,但由于OLP引起的粘膜发炎后变化可能是在受影响的部位色素沉着的原因。

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