Granular cell tumor of the clitoris in the pediatric age. A case report and review of the literature

摘要

Granular cell tumors (GCTs) or Abrikossoff's tumors are rare, soft tissue tumors of neural origin with a generally benign behavior. They can occur anywhere in the body (with up to 7%–16% situated in the vulva) and can occur in patients of any age, being considered rare in children. A 6 year-old girl presented with a clitoral mass, surgically removed. Pathology revealed GCT of clitoris. To our knowledge this is the first case of GCT of the clitoris in the pediatric (prepubertal) age group reported in English literature. Although rare in pediatric age, GCT has to be suspected as a cause of vulvar mass. Surgical treatment and clinical follow-up must consider the possibility of recurrence, multiple location and malignancy with time. Highlights ? Granular cell tumors are uncommon soft tissue tumors of neural origin. ? The tumors may occur in children or adults but are most common in the fourth to sixth decade of life. ? They are seen more often in females than males, being the approximative ratio 3 to 2. ? Vulvar localization of GCT is very uncommon in the pediatric and adolescent age.