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首页> 外文期刊>Journal of Orthopaedic Translation >Development of generic Asian pelvic bone models using CT-based 3D statistical modelling
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Development of generic Asian pelvic bone models using CT-based 3D statistical modelling

机译:使用基于CT的3D统计建模开发通用的亚洲骨盆骨模型

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Background/ObjectiveArtificial bone models (ABMs) are used in orthopaedics for research of biomechanics, development of implants and educational purposes. Most of the commercially available ABMs approximate the morphology of Europeans, but they may not depict the Asian anatomy. Therefore, our aim was to develop the first Asian ABM of the pelvis and compare it with the existing pelvic ABM (Synbone?; Caucasian male).MethodsOne hundred clinical computed tomography (CTs) of adult pelvises (male n??=??50, female n??=??50) of Malay, Chinese and Indian descent were acquired. CTs were segmented and defined landmarks were placed. Three 3D statistical pelvic model and mean models (overall, male, female) were generated. Anatomical variations were analysed using principal component analysis. To measure gender-related differences and differences to the existing ABM, distances between the anterior superior iliac spines (ASIS), the anterior inferior iliac spines (AIIS), the promontory and the symphysis (conjugate vera, CV) as well as the ischial spines (diameter transversa, DT) were quantified.ResultsPrincipal component analysis displayed large variability regarding the pelvic shape and size. Female and male statistical models were similar in ASIS (225??±??20; 227??±??13??mm;P??=??0.4153) and AIIS (185??±??11; 187??±??10??mm;P??=??0.3982) and differed in CV (116??±??10; 105??±??10??mm;P??
机译:背景/目的人工骨模型(ABM)用于整形外科,用于生物力学研究,植入物开发和教育目的。大多数商业上可获得的ABM近似于欧洲人的形态,但它们可能未描绘亚洲人的解剖结构。因此,我们的目标是开发第一个亚洲骨盆ABM,并将其与现有的骨盆ABM(Synbone ?;高加索男性)进行比较。方法:成年骨盆的100项临床计算机断层扫描(CT)(男性n≥50) ,获得了马来人,中国人和印度人后裔的女性n ?? =?50?。 CT被分割并放置了定义的地标。生成了三个3D统计骨盆模型和均值模型(总体,男性,女性)。使用主成分分析法分析解剖变异。为了测量与性别相关的差异以及与现有ABM的差异、,前上棘(ASIS),下前棘(AIIS),海角和耻骨(共轭维拉,CV)以及坐骨棘之间的距离结果:主成分分析显示骨盆形状和大小存在较大差异。女性和男性的统计模型在ASIS(225 ??±?20; 227 ??±?13?mm; P ?? =?0.4153)和AIIS(185?±?11; 187? Δ±Δ10Δθmm; PΔ=Δ0.3982)和CV(116Δ±Δ10;105Δ±Δ10Δmm;PΔ<Δ0.0001)和DT(105≤±θ7;88≤±θ8≤mm;P≤<0.0001)。将男女平等平均模型与既有的ABM,ASIS(226; 275?mm; P ?? <?0.0001),AIIS(186; 209?mm; P?<?0.0001)和CV(111; 105?mm; P ?? <?0.0001)有显着差异。两种模型的DT相似(97; 95?mm; P?=?0.6927)。分析显示亚洲人口中明显的性别和大小相关的解剖变异。华人,马来人和印度人的血统没有显着差异。整个亚洲模式小于现有的ABM。由于亚洲ABM与既有ABM之间存在巨大差异,以及性别之间的差异,使用亚洲和特定性别的ABM导致本文的翻译潜力在针对该人群的研究,生物力学和植入物开发中要考虑的重要因素。

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