Porphyromonas endodontalis in chronic periodontitis: a clinical and microbiological cross-sectional study

摘要

AbstractBackgroundAlthough previous studies have shown the presence of Porphyromonas endodontalis in chronic periodontitis associated with periapical lesions, the occurrence of this pathogen in diseased periodontal sites without periapical lesions has been poorly investigated.ObjectiveThe aims of this study were to quantify P. endodontalis in patients with chronic periodontitis without periapical lesions, to evaluate the potential correlation of P. endodontalis with Porphyromonas gingivalis and Tannerella forsythia, and to evaluate the ability of periodontal treatment to reduce these pathogens.DesignPatients with generalized chronic periodontitis were selected by recording clinical attachment level (CAL), probing depth (PD), and bleeding on probing (BOP). Subgingival samples from 30 diseased nonadjacent sites (CAL?≥?5 mm, PD between 5 and 7 mm and positive BOP) and 30 healthy nonadjacent sites (PD?≤?3 mm and negative BOP) were collected and subjected to microbial analysis by quantitative polymerase chain ...