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首页> 外文期刊>Journal of Oral and Maxillofacial Pathology >Verrucous hyperplasia: A clinico-pathological study
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Verrucous hyperplasia: A clinico-pathological study

机译:疣状增生:临床病理研究

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摘要

Context:Oral verrucous hyperplasia (OVH) is a premalignant lesion that may transform into an oral cancer.Aims:The present retrospective study was carried out to analyze the clinico-pathological features of verrucous hyperplasia (VH).Materials and Methods:Total 19 diagnosed cases of verrucous hyperplasia were retrospectively analyzed for demographic, clinical and histopathological features including dysplasia.Results:Average age of occurrence of lesion was 4 th decade of life, with male predominance (2:1) and common site of occurrence being buccal mucosa. Clinically it present as verrucous exophytic growth with sharp or blunt projections on surface, which corresponds histologically. Tobacco lime quid placement in buccal vestibule was key etiologic factor. Histopathologicaly 68% cases showed dysplasia out of which moderate dysplasia predominates (42%). Moderately dysplastic cases were found to be associated with mixed habit pattern. Maximum cases were treated with excision.Conclusion:Biopsy specimen comprising of adjacent normal epithelium is key in distinguishing verrucous hyperplasia from verrucous carcinoma. Clinical behavior and recurrence potential needs to be assessed with long term follow up studies.
机译:背景:口腔疣状增生(OVH)是一种可能转变为口腔癌的癌前病变。目的:本回顾性研究旨在分析疣状增生(VH)的临床病理特征。材料与方法:共诊断出19例回顾性分析疣状增生病例的人口统计学,临床和组织病理学特征,包括不典型增生。结果:病变的平均发病年龄为生命的第4个十年,男性占优势(2:1),常见的发生部位是颊粘膜。临床上表现为疣状外生性生长,在表面上具有尖锐或钝的突起,这在组织学上是对应的。烟酒在颊前庭的放置是主要的病因。组织病理学研究表明,有68%的病例表现为发育异常,其中以中度发育异常为主(42%)。发现中度异常增生病例与混合习惯模式有关。结论:结论:由正常上皮组成的活检标本是区分疣状增生和疣状癌的关键。临床行为和潜在复发需要通过长期随访研究进行评估。

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