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Nocardia scleritis—clinical presentation and management: a report of three cases and review of literature

机译:诺卡氏硬化症—临床表现和治疗:三例报告并文献复习

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This study aims to describe the clinical features and management of Nocardia scleritis. The authors retrospectively reviewed medical charts of three patients with microbiologically proven Nocardia scleritis and reviewed literature. All the patients presented with areas of well-demarcated, circumscribed abscess. No specific clinical feature could be attributed to the causative organism. Nocardia was identified by smear and culture from the scleral exudates. The medical management was based on the antibiotic sensitivity. Surgical exploration of the suppurated area along with the healthy margins was done on all patients. Two patients required multiple explorations. All three patients resolved with a good visual and tectonic outcome. The literature review also suggests a good outcome with prolonged medical management though the preferred antibiotic has changed over the years. Though the prevalence of a disease like Nocardia scleritis is low, the results suggest that specific diagnosis and appropriate management can lead to a good outcome.
机译:本研究旨在描述诺卡氏硬化症的临床特征和治疗。作者回顾性回顾了三例经微生物学证实的诺卡氏菌硬化症患者的病历,并复习了文献。所有患者均出现界限分明,界限清楚的脓肿区域。没有特定的临床特征可归因于致病菌。通过从巩膜渗出液涂片和培养鉴定出诺卡氏菌。医疗管理基于对抗生素的敏感性。对所有患者进行了化脓区域和健康边缘的手术探查。两名患者需要多次探查。三名患者均获得良好的视觉和构造预后。文献综述还表明,尽管多年来首选的抗生素已发生变化,但延长药物治疗仍可取得良好的疗效。尽管像诺卡氏硬化症这样的疾病的患病率很低,但结果表明,特异性诊断和适当治疗可以带来良好的结果。

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