Transient global amnesia, acute ischemic stroke, seizures and status epilepticus, limbic encephalitis and various types of encephalopathiesare included in differential diagnosis of acute-onset amnestic syndrome. Isolated hippocampal infarction is arare cause of acute-onset amnestic syndrome. In this case presentation, we report a patient who developed permanent andsevere cognitive impairment after acute-onset amnestic syndrome due to bilateral isolated hippocampal infarctions occurringnine months apart and a review of the pertaining literature is presented.
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