Context: Turmeric (Curcuma longa) is a wild plant of the ginger family native to tropical South Asia. Evidence Acquisitions: Directory of Open Access Journals (DOAJ), Google Scholar, Pubmed (NLM), LISTA (EBSCO) and Web of Science have been searched. Results: Emerging evidence indicate that turmeric/curcumin inhibits cytokines and TGF-β production. From the various factors involved in the genesis of chronic kidney disease and pathogenesis of primary and secondary glomerulonehritis, TGF-β has emerged as a key factor in the cascade of events. Leading to glomerulosclerosis, tubulointerstitial fibrosis and end-stage renal disease. Conclusions: considering the inhibitory effect of turmeric/curcumin on cytokines and TGF-β, it seems wise to assume that supplementary turmeric/curcumin might be a candidate remedy for chronic kidney disease and possibly prevention of subsequent end stage renal disease
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机译：背景：姜黄（姜黄）是生于热带南亚的生姜科的野生植物。证据获取：已搜索了开放获取期刊目录（DOAJ），Google Scholar，Pubmed（NLM），LISTA（EBSCO）和Web of Science。结果：新兴证据表明姜黄/姜黄素抑制细胞因子和TGF-β的产生。从参与慢性肾脏疾病的发生以及原发性和继发性肾小球性肾炎发病机理的各种因素来看，TGF-β已成为一系列事件中的关键因素。导致肾小球硬化，肾小管间质纤维化和终末期肾脏疾病。结论：考虑到姜黄/姜黄素对细胞因子和TGF-β的抑制作用，似乎明智的假设是补充姜黄/姜黄素可能是治疗慢性肾脏疾病的候选药物，并可能预防随后的终末期肾脏疾病
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