Effect of different extracts of Stevia rebaudiana leaves on Streptococcus mutans growth

摘要

Plants produce a diverse range of bioactive molecules, making them rich source of different type of medicines. In this study, effect of aqueous, methanol, ethanol and acetone extracts of?Stevia rebaudiana?leaves were evaluated against?Streptococcus mutans. Agar-well diffusion method was used to determine the antibacterial activity of extracts. Minimal inhibitory concentration was obtained by micro-dilution method. The acetone, ethanol and methanol extracts of?S. rebaudiana?leaves exhibited a concentration dependent on antibacterial inhibition. Acetone and ethanol extracts of?Stevia?leaf gave the highest zone of inhibition against?S. mutans. Aqueous extract of this plant was not effective on?S. mutans. Therefore, the findings confirmed the idea that plant extracts of?S. rebaudiana?leaves may have a role to be used as pharmaceuticals and/or preservatives.