> In this study, the derivation of mathematical model for the wave modulation through an incompressible viscous fluid contained in a prestressed thin stenosed elastic tube is presented. The artery is assumed to be incompressible, prestressed thin walled elastic tube with a symmetrical stenosis, whereas the blood is considered to be incompressible and Newtonian fluid. By utilizing the nonlinear equations of tube and fluid, the weakly nonlinear wave modulation in such a medium is examined. Employing the reductive perturbation method and considering the long-wave approximation, we showed that the third-order term in the perturbation expansion is governed by the dissipative nonlinear Schrodinger equation with variable coefficient. Our results shown that this type of equation admits a downward bell-shape wave propagates to the right as time increases with decreasing wave amplitude.
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