Desensitization to Filgrastim in a 2-Year-Old Girl With a Vaginal Endodermal Sinus Tumor

摘要

Recombinant human granulocyte-stimulating factors (G-CSF) are administered to cancer patients to minimize the intensity and duration of neutropenia associated with chemotherapy and radiotherapy. The commercially available members of this family in Spain are filgrastim (Neupogen, Amgen SA), lenograstim (Granocyte, Italfarmaco SA), and pegfilgrastim (Neulasta, Amgen SA).