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Maternal hyperglycemia during labor and related immediate post-partum maternal and perinatal outcomes at the Yaoundé Central Hospital, Cameroon

机译:喀麦隆雅温得中心医院分娩期间的母体高血糖症以及相关的产后立即产妇和围产儿结局

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Background Data on the prevalence and complications of gestational diabetes are very scarce in Cameroon. The aim of this study was to evaluate the uptake of screening for gestational diabetes and assess the immediate post-partum outcome of hyperglycemic parturient mothers and perinatal outcome of their babies. Methods A prospective cohort study was held at the Maternity of the Yaoundé Central Hospital from March to June 2013. One hundred volunteer women in labor without overt diabetes mellitus and having fasted for 8 to 12?h were recruited. No intervention was given. A clinical examination was done and capillary glucose recorded. Parturient women were categorized into two groups (hyperglycemic and non-hyperglycemic subjects) based on glycemia results interpreted according to the International Association of Diabetes and Pregnancy Study Groups. Mothers’ clinical examination was repeated and neonates examined immediately after delivery. Perinatal outcomes associated with maternal hyperglycemia during labor were assessed using relative risks. A p value <0.05 was considered statistically significant. Results One hundred women with a mean age of 27 (SD 6) years were recruited. Of them, 22 (22?%) had already been screened for gestational diabetes at baseline. Thirty-one (31?%) were diagnosed with hyperglycemia during labor, and this condition was highly associated with macrosomia in neonates (RR?=?8.9, 95?% CI 2.70–29.32; p
机译:在喀麦隆,关于妊娠糖尿病的患病率和并发症的背景资料非常少。这项研究的目的是评估妊娠糖尿病筛查的摄取率,并评估高血糖分娩母亲的产后即时结果及其婴儿的围产期结果。方法2013年3月至2013年6月,在雅温得中心医院的产妇进行了一项前瞻性队列研究。招募了100名无明显糖尿病且禁食8至12h的志愿妇女。没有干预。进行了临床检查并记录了毛细血管葡萄糖。根据国际糖尿病和妊娠研究小组解释的血糖结果,将产妇分为两类(高血糖和非高血糖受试者)。重复母亲的临床检查,分娩后立即检查新生儿。使用相对风险评估与分娩期间孕妇高血糖相关的围产期结局。 p值<0.05被认为具有统计学意义。结果招募了100名平均年龄为27(SD 6)岁的女性。他们中有22名(22%)已在基线时筛查了妊娠糖尿病。劳动中被诊断出高血糖症的人为31人(31%),这种情况与新生儿的巨大儿症高度相关(RR?=?8.9,95%CI 2.70-29.32; p <?0.001)。分娩时与母体高血糖症相关的其他并发症包括会阴撕裂,剖宫产和宫内胎儿死亡,尽管这种关联在统计学上不显着。结论这项研究的主要发现是分娩期间的母体高血糖与新生儿巨大儿有关。大约三分之一的母亲在分娩过程中担心高血糖,并且在该系列中未对妊娠糖尿病进行足够的筛查。

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