Effects of bifidobacterium-containing enteral nutrition intervention on the nutritional status and intestinal flora disturbance in patients with the severe cerebral infarction

摘要

Objective: To study the effects of bifidobacterium-containing enteral nutrition interventionon the nutritional status and intestinal flora disturbance in patients with the severe cerebralinfarction. Methods: 88 patients with severe cerebral infarction who were treated in DeyangSecond People’s Hospital between March 2014 and October 2016 were collected and dividedinto control group and observation group according to the random number table, controlgroup received routine enteral nutrition intervention, and the observation group receivedbifidobacterium-containing enteral nutrition intervention. The nutritional status, intestinalmucosa function and intestinal flora distribution before and after nutritional interventionwere compared between the two groups of patients. Results: Before intervention, differencesin the nutritional status, intestinal mucosa function and intestinal flora distribution were notstatistically significant between two groups of patients. After intervention, peripheral bloodlevels of nutritional status indexes Hb, TP, ALB, PA and TF in observation group were higherthan those in control group; serum levels of intestinal mucosal barrier function indexesDAO and D-lactate were lower than those in control group; the number of bifidobacteriumand lactobacillus in feces were larger than those in control group while the number ofenterobacteria and enterococcus were smaller than those in control group. Conclusion:Bifidobacterium-containing enteral nutrition intervention can enhance the nutritional status,optimize the intestinal mucosa function and reduce the intestinal flora disturbance in patientswith severe cerebral infarction.