Evaluation value of three-dimensional finite element model analysis for bone mineral density and bone metabolism activity in patients with osteoporosis

摘要

Objective: To study the evaluation value of three-dimensional finite element model analysisfor bone mineral density (BMD) and bone metabolism activity in patients with osteoporosis.Methods: A total of 218 patients who were diagnosed with osteoporosis in the hospitalbetween February 2014 and January 2017 were collected as observation group, and 100healthy volunteers who received physical examination in the hospital during the same periodwere selected as normal control group. The femoral head of the two groups was analyzed bythree-dimensional finite element model, and the femoral head BMD levels and serum bonemetabolism index contents were measured. Pearson test was used to evaluate the evaluationvalue of femoral head three-dimensional finite element model for osteoporosis. Results: Thecancellous bone and cortical bone Von Mises stress value of observation group were lower thanthose of normal control group, and femoral neck BMD value of observation group was lowerthan that of normal control group; serum bone metabolism index BGP content was lower thanthat of normal control group while NBAP, TRACP-5b and CTX-1 contents were higher thanthose of normal control group. Pearson test showed that the cancellous bone and cortical boneVon Mises stress value of patients with osteoporosis were directly correlated with BMD valueand bone metabolism index contents. Conclusion: The three-dimensional finite element modelanalysis resultsof patients with osteoporosis can objectively reflect the femoral headBMDvalue and bone metabolism activity, and is a reliable way to evaluate the risk of long-termfractures.