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Hospitalization Events Among Sickle Cell Anemia Patients at Homabay County Referral Hospital, Western Kenya

机译:肯尼亚西部霍马贝县转诊医院镰状细胞性贫血患者的住院事件

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Approximately 700,000 new cases of sickle-cell anemia (SCA) occur annually in the world with 60%-80% dying before their 5 th year birthday. SCA patients often experience hospitalization events including admissions for pain and vaso-occlusive crisis, infections and blood transfusions. However, limited studies have evaluated these events to improve comprehensive care programs. A descriptive cross-sectional study design was adopted on 227 SCA patients receiving healthcare between January 2017 and December 2017 at Homabay County Referral Hospital, Western Kenya. A complete enumeration sampling technique was used, and data was collected from hospital medical records. A total of 167 (73.57%) SCA patients were admitted to the hospital, 64 (38.32%) had pain and vaso-occlusive crisis (PVC), 47 (28.14%) malaria infection and others had combination of infections or conditions. SCA patients with malaria had increased chance of admission (12.86% CI; 5.36-30.85%. P value <0.0001) and blood transfusions (11.67% CI; 5.27-25.82%, P value <0.0001). In addition, less than 20% were given drugs at the time of discharge suggesting unavailability of drugs. PVC is the leading cause of hospitalization and malaria infection prolong the period of admission and increases blood transfusions among SCA patients. The study provides important information on the need for improved care for PVC and enhanced malaria intervention among SCA patients.
机译:全世界每年约有70万新的镰状细胞性贫血(SCA)病例发生,其中60%-80%在其5岁生日之前死亡。 SCA患者经常经历住院事件,包括因疼痛和血管闭塞性危机而住院,感染和输血。但是,有限的研究评估了这些事件,以改善综合护理计划。在2017年1月至2017年12月期间,对肯尼亚西部Homabay县转诊医院的227名接受医疗保健的SCA患者采用了描述性横断面研究设计。使用了完整的枚举采样技术,并从医院病历中收集了数据。共有167名(73.57%)SCA患者入院,其中64名(38.32%)患有疼痛和血管闭塞性危机(PVC),47名(28.14%)疟疾感染,而其他人则合并了感染或病情。患有疟疾的SCA患者有更高的入院机会(12.86%CI; 5.36-30.85%。P值<0.0001)和输血(11.67%CI; 5.27-25.82%,P值<0.0001)。另外,出院时不到20%的人服用了药物,表明没有药物。 PVC是住院的主要原因,疟疾感染会延长住院时间并增加SCA患者的输血量。该研究提供了重要信息,说明在SCA患者中需要改善对PVC的护理和加强疟疾干预。

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