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首页> 外文期刊>Journal of Experimental Life Science >Dynamical Analysis of HIV/AIDS Epidemic Model with Treatment
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Dynamical Analysis of HIV/AIDS Epidemic Model with Treatment

机译:HIV / AIDS流行病模型治疗的动力学分析

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摘要

In this article, an epidemic model of HIV/AIDS with treatment is observed. This model consists of five populations: susceptible, educated susceptible, exposed, HIV infected, and AIDS infected. Antiretroviral therapy (ART) is one type of treatment that can be given to individual that is infected by HIV. This medication can prevent the growth of the virus. Exposed individuals are given short-term antiretroviral treatment called Post Exposure Prophylaxis (PPP), while for infected individuals are given treatment by combining two or three types of antiretroviral drugs. Dynamical analysis is performed by determining equilibrium points and local stability analysis. Based on the analysis results, two equilibrium points are obtained, namely disease-free equilibrium point and endemic equilibrium points. The stability analysis shows that the free equilibrium point is locally asymptotically stable if 15R01"> ?and the endemic equilibrium point is locally asymptotically stable under certain conditions. Numerical simulations show that giving two medications together has a greater effect in reducing the spread of the disease.Keywords: antiretroviral, dynamical analysis, HIV/AIDS.
机译:在本文中,观察到了带有治疗方法的艾滋病毒/艾滋病流行模型。该模型由五个人群组成:易感人群,受过教育的易感人群,暴露人群,HIV感染者和AIDS感染者。抗逆转录病毒疗法(ART)是可以对感染HIV的个体进行的一种治疗。这种药物可以防止病毒的生长。对受感染的个体进行短期的抗逆转录病毒治疗,称为暴露后预防(PPP),而对受感染的个体则通过组合两种或三种抗逆转录病毒药物进行治疗。通过确定平衡点和局部稳定性分析来进行动力学分析。根据分析结果,获得了两个平衡点,即无病平衡点和地方性平衡点。稳定性分析表明,如果在一定条件下15R0 <1>,自由平衡点是局部渐近稳定的,地方病平衡点在某些条件下是局部渐近稳定的,数值模拟表明,将两种药物一起使用对减少药物的扩散具有更大的作用。关键字:抗逆转录病毒,动力学分析,HIV / AIDS。

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