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Obesity paradox on the survival of elderly patients with diabetes: an AHAP-based study

机译:肥胖悖论对老年糖尿病患者生存的影响:一项基于AHAP的研究

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Background and objectivesOverweight and obesity are among the important challenges in health issues and survival of elderly people. The current study aimed to evaluate the survival rate of elderly patients with diabetes, and its influencing factors, on the basis of body mass index (BMI). Methods and materialsThe design of the current study was based on the Amirkola Health and Aging Project (AHAP) cohort. The 5–year survival rate of elderly people with diabetes and the factors that influence the mortality rate by Cox regression model were analyzed. ResultsOut of 1616 elderly people who were evaluated in the current study, 501 (31%) had diabetes. The results showed that diabetes significantly increased the mortality rate (adjusted hazard ratio [HR]?=?2.10; 95% confidence interval [CI]: 1.57–2.81; P ConclusionAlthough overweight and obesity significantly improved the risk of mortality in elderly patients with diabetes, central obesity is still considered as an important risk factor.
机译:背景和目标超重和肥胖是老年人健康问题和生存的重要挑战。本研究旨在根据体重指数(BMI)评估老年糖尿病患者的生存率及其影响因素。方法和材料本研究的设计基于Amirkola健康与衰老项目(AHAP)队列。通过Cox回归模型分析了老年糖尿病患者的5年生存率以及影响死亡率的因素。结果在本研究中评估的1616位老年人中,有501位(31%)患有糖尿病。结果表明,糖尿病显着提高了死亡率(调整后的危险比[HR]?=?2.10; 95%置信区间[CI]:1.57-2.81; P结论)尽管超重和肥胖症可以显着提高老年糖尿病患者的死亡风险,中枢性肥胖仍被认为是重要的危险因素。

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