Importance of nonspecific laboratory tests in Brucella diagnosis

摘要

Objectives:Brucella infection doesn't have spesific clini-cal evidences, for this reason it can be confused with fe-brile diseases. In this study we aimed investigating the importance of diagnosis with nonspesific laboratory tests in brucellosis.Materials and methods: We retrospectively screened clinically compatible with brucellosis, standard tube ag-glutination (STA) and STA tests with coombs of patients sera which came to U.ak State Hospital Central Labo-ratory between December 2010-May 2011. As control group, we determined random 62 patients attended to the laboratory between December 2010-May 2011 with STA test results are negative and not diagnosed brucellosis.Results:C-reactive protein elevated in 54 patients (87.0%), ESR elevated in 44 patients (70.9%), AST el-evated in 22 patients (35.4%), ALT elevated in 7 patients (11.2%), ferritin elevated in 19 patients (30.6%), 8 patients had anemia (12.9%) of patient group. In control group, 7 patients elevated CRP (11.2%), 10 patients elevated ESR (16.1%), 1 patient elevated AST (1.6%), 1 patient elevated ALT (1.6%), 6 patients had anemia (9.6%) and decrease in ferritin level wasn't detected. Conclusion:We concluded statistically significant high level of CRP, ESR, ALT, AST and ferritin support the test results too beside the spesific brucellosis tests