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Universal or selective ultrasound screening for developmental dysplasia of the hip? A discussion of the key issues

机译:通用或选择性超声筛查髋关节发育不良?关键问题的讨论

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Purpose To summarize recent developments and provide recommendations as to whether universal or selective programmes are advisable. Methods A literature review was performed and preference given to studies with higher levels of evidence. All programmes reviewed included clinical screening. Results Recent studies underline the need for high quality screening programmes to promote the early detection of developmental dysplasia of the hip (DDH). A small number of cases may be missed clinically but with universal ultrasound screening programmes the late presentation rates appear to be virtually zero. Contemporary studies show treatment rates with universal screening programmes which are now lower than those with selective ultrasound. There is little agreement over the criteria used for selective programmes. Alternative outcome measures, such as the first operation rate or the percentage undergoing major (open) surgery are both lowest with universal ultrasound screening programmes. Furthermore, a significant reduction in the rate of surgery for DDH later in life was seen after the introduction of universal ultrasound screening, whereas the defined criteria for selective screening may not detect the majority of patients who require late surgery. Abduction bracing with modern orthoses is associated with a zero rate of avascular necrosis (AVN), whereas closed reduction techniques have an overall risk of 10%. Conclusion On clinical grounds, if future studies confirm that hip abduction in flexible orthoses is not associated with AVN, it may be time for a paradigm shift of screening for DDH towards a universal ultrasound protocol. The costs associated both with each type of screening programme and with the management of late presenting cases are also important but may be secondary to clinical benefit.
机译:目的总结最近的发展并就普遍计划或选择性计划提供建议。方法进行文献综述,并优先选择证据水平较高的研究。审查的所有程序均包括临床筛查。结果最近的研究强调需要高质量的筛查程序,以促进早期发现髋关节发育不良(DDH)。少数病例在临床上可能会漏诊,但使用通用超声筛查程序,晚期出现率似乎几乎为零。当代研究表明,通用筛查程序的治疗率现在低于选择性超声的治疗率。对于选择性方案所使用的标准几乎没有共识。通用超声筛查程序可替代的结局指标,例如首次手术率或接受大手术(开放手术)的百分比,都是最低的。此外,在引入通用超声筛查后,发现生命后期DDH的手术率显着降低,而选择性筛查的既定标准可能无法检测到大多数需要后期手术的患者。采用现代矫形器进行外展支撑与无血管坏死(AVN)的零发生率相关,而封闭复位术的总风险为10%。结论从临床的角度来看,如果将来的研究证实柔性矫形器中的髋关节外展与AVN无关,那么可能是将DDH筛查向通用超声方案转变的时候了。与每种类型的筛查程序以及与晚期病例的管理相关的费用也很重要,但可能次于临床。

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