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首页> 外文期刊>Journal of Cardiothoracic Surgery >Early malperfusion, ischemia reperfusion injury, and respiratory failure in acute complicated type B aortic dissection after thoracic endovascular repair
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Early malperfusion, ischemia reperfusion injury, and respiratory failure in acute complicated type B aortic dissection after thoracic endovascular repair

机译:胸腔内修复后并发急性复杂B型主动脉夹层的早期灌注异常,缺血再灌注损伤和呼吸衰竭

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Background The aim of this study was to determine the early mortality and major complications of acute complicated type B aortic dissection (ACBD) after thoracic endovascular aortic repair (TEVAR). Methods Twenty-six consecutive patients with ACBD who underwent TEVAR were included. Clinical indications before TEVAR and in-hospital mortality and major complications after TEVAR were analyzed and compared with similar reports. Results TEVAR was technically successful in all cases. In-hospital mortality occurred in four patients (15%), and major complications occurred in an additional four patients (15%). Three of the four (75%) of the deaths were associated with malperfusion and ischemia reperfusion injury (IRI), and 3/4 (75%) of the major complications were caused by respiratory failure (RF). Conclusions In-hospital mortality associated strongly with severe end-organ malperfusion and IRI, while major complications associated with RF, during TEVAR. Our results indicate that malperfusion, IRI and respiratory failure during TEVAR should be carefully monitored and aggressively treated.
机译:背景技术这项研究的目的是确定胸腔内血管主动脉修复(TEVAR)后急性复杂B型主动脉夹层(ACBD)的早期死亡率和主要并发症。方法纳入26例接受TEVAR的ACBD连续患者。分析TEVAR之前的临床指征以及TEVAR之后的院内死亡率和主要并发症,并将其与类似报道进行比较。结果TEVAR在所有情况下在技术上都是成功的。院内死亡发生在四名患者(15%)中,主要并发症发生在另外四名患者(15%)中。死亡的四分之三(75%)与灌注不良和缺血再灌注损伤(IRI)有关,主要并发症的3/4(75%)是由呼吸衰竭(RF)引起的。结论TEVAR期间院内死亡率与严重的终末器官灌注异常和IRI密切相关,而主要并发症与RF相关。我们的结果表明,应认真监测和积极治疗TEVAR期间的灌注不足,IRI和呼吸衰竭。

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