Assessment of the Inhibitory Mechanism of Action for a Yeast Cell-based Screening System Targeting Glycogen Synthase Kinase-3β (GSK-3β)

摘要

Background and Objective: Glycogen Synthase Kinase-3 (GSK-3) is one of the prior targets for drug discovery due to its involvement in many cell signaling and metabolism. It has been implicated in several critical diseases such as diabetes, Alzheimer?s dis