A Novel Therapeutic Lotion For TreatingAlopecia Using Medicinal Plant Extracts andits Effects on Human Hormone Profiles

摘要

Objectives: To examine the action of a novel composite lotion of medicinal plants extract for treatment of Alopecia and to outline its effects on human hormones profile. Design and Methods: Eighty four volunteers were enrolled in the prospective study. The new composite lotion was prepared by mixing the following components: Polar solvent extract of medicinal herb, Polypeptide compounds including keratin and keratin derivatives, and Methionine. These components were mixed in a ratio 5: 0.5: 0.1; respectively. All patients were advised to use the new composite lotion to be applied on the scalp skin once, twice daily or every other day for a period of four to six months. Moreover, hormones levels were measured using ELISA procedure. Results: After treatment, revealed cessation of hair loss while starting stimulation of inactive hair follicle and hence, hair growth. Moreover, the current study resulted that the novel product has no effects on hormones profile. Conclusion: These pharmaceutical achievements may be a result of stimulation of an inactive hair follicle or modulating the dysfunction of the hair follicles or by improving the general physiological status of the scalp skin while no any drawback was observed for the hormones profile.