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Development of a dose verification system for Vero4DRT using Monte Carlo method

机译:使用蒙特卡洛方法开发用于Vero4DRT的剂量验证系统

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Vero4DRT is an innovative image-guided radiotherapy system employing a C-band X-ray head with gimbal mechanics. The purposes of this study were to propose specific MC models of the linac head and multileaf collimator (MLC) for the Vero4DRT and to verify their accuracy. For a 6 MV photon beam delivered by the Vero4DRT, a simulation code was implemented using EGSnrc. The linac head model and the MLC model were simulated based on its specification. Next, the percent depth dose (PDD) and beam profiles at depths of 15, 100, and 200 mm were simulated under source-to-surface distance of 900 and 1000 mm. Field size was set to 150 × 150 mm 2 at a depth of 100 mm. Each of the simulated dosimetric metrics was then compared with the corresponding measurements by a 0.125 cc ionization chamber. After that, intra- and interleaf leakage, tongue-and-groove, and rounded-leaf profiles were simulated for the static MLC model. Meanwhile, film measurements were performed using EDR2 films under similar conditions to simulation. The measurement for the rounded-leaf profile was performed using the water phantom and the ionization chamber. The leaf physical density and abutting leaf gap were adjusted to obtain good agreement between the simulated intra- and interleaf leakage profiles and measurements. For the MLC model in step-and-shoot cases, a pyramid and a prostate IMRT field were simulated, while film measurements were performed using EDR2. For the linac head, exclusive of MLC, the difference in PDD was 1.0 % after the buildup region. The simulated beam profiles agreed to within 1.3% at each depth. The MLC model has been shown to reproduce dose measurements within 2.5% for static tests. The MLC is made of tungsten alloy with a purity of 95%. The leaf gap of 0.015 cm and the MLC physical density of 18.0 g / cm 3 , which provided the best agreement between the simulated and measured leaf leakage, were assigned to our MC model. As a result, the simulated step-and-shoot IMRT dose distributions agreed with the film measurements to within 3.3%, with exception of the penumbra region. We have developed specific MC models of the linac head and the MLC in the Vero4DRT system. The results have demonstrated that our MC models have high accuracy.PACS numbers: 87.55.K-, 87.56.nk, 87.56.bd
机译:Vero4DRT是一种创新的图像引导放射治疗系统,采用具有云台机制的C波段X射线头。这项研究的目的是为Vero4DRT提出直线加速器头部和多叶准直仪(MLC)的特定MC模型并验证其准确性。对于Vero4DRT传送的6 MV光子束,使用EGSnrc实现了仿真代码。直线加速器头部模型和MLC模型是根据其规格进行模拟的。接下来,在源到表面距离为900和1000 mm的情况下,模拟了15、100和200 mm深度处的深度剂量百分比(PDD)和光束轮廓。在100mm的深度处将场尺寸设置为150×150 mm 2。然后通过0.125 cc电离室将每个模拟的剂量学度量与相应的测量进行比较。此后,针对静态MLC模型模拟了叶内和叶间泄漏,舌沟和圆形叶轮廓。同时,在与模拟相似的条件下使用EDR2膜进行膜测量。圆形叶片轮廓的测量是使用水体模和电离室进行的。调节叶片的物理密度和邻接的叶片间隙,以使模拟的叶内和叶间泄漏曲线与测量值之间取得良好的一致性。对于分步拍摄的MLC模型,模拟了金字塔和前列腺IMRT场,而使用EDR2进行了胶片测量。对于直线加速器头部(不包括MLC),在堆积区域之后,PDD的差异为1.0%。在每个深度处,模拟的光束轮廓均在1.3%以内。对于静态测试,MLC模型已显示出在2.5%以内的剂量测量结果。 MLC由钨合金制成,纯度为95%。将0.015 cm的叶片间隙和18.0 g / cm 3的MLC物理密度(在模拟的和测量的叶片泄漏之间提供了最佳的一致性)分配给我们的MC模型。结果,除了半影区域以外,模拟的逐次冲量IMRT剂量分布与胶片测量值相吻合在3.3%以内。我们已经开发了Vero4DRT系统中直线加速器头部和MLC的特定MC模型。结果表明,我们的MC模型具有较高的精度.PACS编号:87.55.K-,87.56.nk,87.56.bd

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