首页> 外文期刊>Journal of applied clinical medical physics / >Comparison of planning techniques when air/fluid is present using the strut‐adjusted volume implant (SAVI) for HDR‐based accelerated partial breast irradiation
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Comparison of planning techniques when air/fluid is present using the strut‐adjusted volume implant (SAVI) for HDR‐based accelerated partial breast irradiation

机译:当使用基于HDR的加速局部乳房照射的支撑架调整体积植入物(SAVI)时存在空气/流体时的计划技术比较

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The presence of air/fluid surrounding implantable devices used for partial breast irradiation may significantly impact dose coverage to at‐risk tissue. Of the 67 total patients retrospectively evaluated for this study, 32 (48%) had greater than 1 cc volume of air/fluid extending outside of the strut‐adjusted volume implant (SAVI) device surface and were selected for comparison of planning approaches. The planning approaches utilized two different definitions of PTV_EVAL. One definition of a PTV_EVAL was based on expanding 1 cm beyond the SAVI device only while accounting for the air/fluid using the NSABP Protocol B‐39/RTOG Protocol 0413. The second PTV_EVAL definition was based on expanding 1 cm beyond the cavity (SAVI device plus air/fluid volume). The results indicate use of the B‐39 formalism to account for air/fluid displacing the PTV_EVAL may overestimate the dose coverage to the at‐risk tissue, especially for large contiguous volumes of air/fluid. Using the SAVI device to optimize dose covering the volume surrounding the cavity improves dosimetric coverage to at‐risk tissue by 11.3% and 8.7% for V100 and V90, respectively, while the average V150 and V200 indices for increased by 9.1 cc and 5.0 cc, respectively, and the average maximum rib and skin doses increased by 11. 1% and 6.1%, respectively. The maximum skin dose, rib dose, V150, and V200 all met the planning objectives despite any increase in these parameters. PACS number: 87.55.kh
机译:用于部分乳房照射的可植入设备周围的空气/流体的存在可能会严重影响高风险组织的剂量覆盖率。在本研究的回顾性评估的67例患者中,有32例(48%)的空气/流体体积大于1 cc,并从支杆调整体积植入物(SAVI)设备表面向外延伸,并被选择用于比较计划方法。规划方法利用了PTV_EVAL的两个不同定义。 PTV_EVAL的一个定义是仅在使用NSABP协议B-39 / RTOG协议0413计入空气/流体的基础上,将SAVI设备扩展1 cm。设备加空气/流体量)。结果表明,使用B-39形式主义来说明空气/流体置换PTV_EVAL可能会高估风险组织的剂量范围,尤其是对于大量连续的空气/流体。使用SAVI设备优化覆盖腔体周围空间的剂量后,对于V100和V90,处于危险组织的剂量覆盖率分别提高了11.3%和8.7%,而平均V150和V200指数分别提高了9.1 cc和5.0 cc,平均最大肋骨和皮肤剂量分别增加了11. 1%和6.1%。尽管这些参数有所增加,但最大皮肤剂量,肋骨剂量,V150和V200均达到了计划目标。 PACS编号:87.55.kh

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