首页> 美国卫生研究院文献>Journal of Applied Clinical Medical Physics >Comparison of planning techniques when air/fluid is present using the strut‐adjusted volume implant (SAVI) for HDR‐based accelerated partial breast irradiation
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Comparison of planning techniques when air/fluid is present using the strut‐adjusted volume implant (SAVI) for HDR‐based accelerated partial breast irradiation

机译:当使用基于HDR的加速局部乳房照射的支撑架调整型植入物(SAVI)时存在空气/流体时的计划技术比较

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摘要

The presence of air/fluid surrounding implantable devices used for partial breast irradiation may significantly impact dose coverage to at‐risk tissue. Of the 67 total patients retrospectively evaluated for this study, 32 (48%) had greater than 1 cc volume of air/fluid extending outside of the strut‐adjusted volume implant (SAVI) device surface and were selected for comparison of planning approaches. The planning approaches utilized two different definitions of PTV_EVAL. One definition of a PTV_EVAL (PTV_EVALSAVI) was based on expanding 1 cm beyond the SAVI device only while accounting for the air/fluid using the NSABP Protocol B‐39/RTOG Protocol 0413. The second PTV_EVAL definition (PTV_EVALCAV) was based on expanding 1 cm beyond the cavity (SAVI device plus air/fluid volume). The results indicate use of the B‐39 formalism to account for air/fluid displacing the PTV_EVAL may overestimate the dose coverage to the at‐risk tissue, especially for large contiguous volumes of air/fluid. Using the SAVI device to optimize dose covering the PTV_EVALCAV volume surrounding the cavity improves dosimetric coverage to at‐risk tissue by 11.3% and 8.7% for V100 and V90, respectively, while the average V150 and V200 indices for PTV_EVALCAV increased by 9.1 cc and 5.0 cc, respectively, and the average maximum rib and skin doses increased by 11. 1% and 6.1%, respectively. The maximum skin dose, rib dose, V150, and V200 all met the planning objectives despite any increase in these parameters.PACS number: 87.55.kh
机译:用于部分乳房照射的可植入设备周围的空气/流体的存在可能会严重影响高危组织的剂量覆盖率。在本研究的回顾性评估的67例患者中,有32例(48%)的空气/流体体积大于1 cc,并从支杆调整体积植入物(SAVI)装置的表面向外延伸,并被选择用于比较计划方法。规划方法利用了PTV_EVAL的两个不同定义。 PTV_EVAL的一种定义 PTV _ EVAL SAVI 的依据是仅在使用NSABP协议B-39 / RTOG协议0413考虑空气/流体的同时将SAVI设备扩展1厘米。第二个PTV_EVAL定义 PTV _ EVAL CAV 是基于将腔体扩展1厘米(SAVI设备加上空气/流体体积)。结果表明,使用B-39形式主义来说明PTV_EVAL的空气/流体位移可能会高估风险组织的剂量范围,尤其是对于大量连续的空气/流体。使用SAVI设备优化覆盖 的剂量 PTV _ EVAL CAV 卷V100和V90的腔体使对危险组织的剂量覆盖率分别提高了11.3%和8.7%,而 PTV _ EVAL CAV 分别增加了9.1 cc和5.0 cc,平均最大肋骨和皮肤剂量分别增加了11、1%和6.1%。尽管增加了这些参数,但最大皮肤剂量,肋骨剂量,V150和V200均达到了计划目标.PACS编号:87.55.kh

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