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Improving accuracy for stereotactic body radiotherapy treatments of spinal metastases

机译:立体定向放射疗法治疗脊柱转移瘤的准确性提高

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Purpose Use of SBRT techniques is now a relatively common recourse for spinal metastases due to good local control rates and durable pain control. However, the technique has not yet reached maturity for gantry‐based systems, so work is still required in finding planning approaches that produce optimum conformity as well as delivery for the slew of treatment planning systems and treatment machines. Methods A set of 32 SBRT spine treatment plans based on four vertebral sites, varying in modality and number of control points, were created in Pinnacle. These plans were assessed according to complexity metrics and planning objectives as well as undergoing treatment delivery QA on an Elekta VersaHD through ion chamber measurement, ArcCheck, film‐dose map comparison and MLC log‐file reconstruction via PerFraction. Results All methods of QA demonstrated statistically significant agreement with each other ( r =?0.63, P ?0.05) but improved with the number of control points ( r =?0.46, P ?0.05) but rather more complexly modulated plans showed poorer results due to MLC leaf position inaccuracies. Plans utilizing 180 and 240 control points produced optimal plan coverage with similar complexity metrics to each other. However, plans with 240 control points demonstrated slightly better delivery accuracy, with fewer MLC leaf position discrepancies. Conclusion In contrast to other studies, MU had no effect on delivery accuracy, with the most impactful parameter at the disposal of the planner being the number of control points utilized.
机译:目的由于良好的局部控制率和持久的疼痛控制能力,SBRT技术现在已成为脊柱转移的相对普遍的求助手段。但是,该技术尚未在基于龙门架的系统上达到成熟,因此仍需要寻找能够产生最佳一致性以及为大量治疗计划系统和治疗机器提供服务的计划方法的工作。方法在Pinnacle中创建了一套基于四个椎骨部位的32份SBRT脊柱治疗计划,这些计划的方式和控制点数量不同。这些计划是根据复杂性指标和计划目标以及通过离子室测量,ArcCheck,胶片剂量图比较以及通过PerFraction进行的MLC日志文件重建在Elekta VersaHD上进行的治疗交付质量保证进行评估的。结果所有质量保证方法均显示出统计学上的显着一致性(r =?0.63,P <0.05),但随着控制点数量的改善(r =?0.46,P <0.05),但更复杂的调制方案显示出较差的结果到MLC叶片位置不正确。利用180个控制点和240个控制点的计划产生了具有彼此相似的复杂性指标的最佳计划覆盖范围。但是,具有240个控制点的计划显示出更好的交付准确性,而MLC叶片位置差异较少。结论与其他研究相比,MU对交付准确性没有影响,规划者可以使用的最有影响力的参数是所利用的控制点数量。

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