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Dosimetry of small bone joint calculated by the analytical anisotropic algorithm: a Monte Carlo evaluation using the EGSnrc

机译:解析各向异性算法计算的小骨关节剂量:使用EGSnrc的蒙特卡洛评估

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This study compared a small bone joint dosimetry calculated by the anisotropic analytical algorithm (AAA) and Monte Carlo simulation using megavoltage (MV) photon beams. The performance of the AAA in the joint dose calculation was evaluated using Monte Carlo simulation, and dependences of joint dose on its width and beam angle were investigated. Small bone joint phantoms containing a vertical water layer (0.5-2 mm) sandwiched by two bones ( 2 × 2 × 2 cm 3 ) were irradiated by the 6 and 15 MV photon beams with field size equal to 4 × 4 cm 2 . Depth doses along the central beam axis in a joint (cartilage) were calculated with and without a bolus ( thickness = 1.5 cm ) added on top of the phantoms. Different beam angles (0°-15°) were used with the isocenter set to the center of the bone joint for dose calculations using the AAA (Eclipse treatment planning system) and Monte Carlo simulation (the EGSnrc code). For dosimetry comparison and normalization, dose calculations were repeated in homogeneous water phantoms with the bone substituted by water. Comparing the calculated dosimetry between the AAA and Monte Carlo simulation, the AAA underestimated joint doses varying with its widths by about 6%-12% for 6 MV and 12%-23% for 15 MV without bolus, and by 7% for 6 MV and 13%-17% for 15 MV with bolus. Moreover, joint doses calculated by the AAA did not vary with the joint width and beam angle. From Monte Carlo results, there was a decrease in the calculated joint dose as the joint width increased, and a slight decrease as the beam angle increased. When bolus was added to the phantom, it was found that variations of joint dose with its width and beam angle became less significant for the 6 MV photon beams. In conclusion, dosimetry deviation in small bone joint calculated by the AAA and Monte Carlo simulation was studied using the 6 and 15 MV photon beam. The AAA could not predict variations of joint dose with its width and beam angle, which were predicted by the Monte Carlo simulations.PACS numbers: 87.55.K-; 87.53.Bn; 87.53.-j
机译:这项研究比较了各向异性分析算法(AAA)和使用兆伏(MV)光子束的蒙特卡罗模拟计算的小骨关节剂量。使用蒙特卡洛模拟评估了AAA在关节剂量计算中的性能,并研究了关节剂量对其宽度和束角的依赖性。用场大小等于4×4 cm 2的6和15 MV光子束照射包含垂直水层(0.5-2 mm)并夹在两根骨头(2×2×2 cm 3)中的小骨关节体模。计算在假体顶部添加和不添加推注(厚度= 1.5 cm)的情况下,关节(软骨)中沿中心光束轴的深度剂量。使用等角点设置为骨关节中心的不同束角(0°-15°),以使用AAA(Eclipse治疗计划系统)和Monte Carlo模拟(EGSnrc代码)进行剂量计算。为了进行剂量学比较和归一化,在均质水体模中重复剂量计算,骨骼被水取代。比较AAA和Monte Carlo模拟之间的计算剂量,AAA低估了关节剂量,其剂量变化对6 MV约为6%-12%,对不带推注的15 MV约为12%-23%,对6 MV约为7%。 15 MV推注时为13%-17%。此外,由AAA计算的关节剂量不会随关节宽度和束角而变化。从蒙特卡洛结果来看,随着关节宽度的增加,计算出的关节剂量会减少,而随着束角的增加,关节剂量会略有减少。当将推注物添加到体模时,发现对于6 MV光子束,关节剂量随其宽度和束角的变化变得不那么明显。总之,使用6和15 MV光子束研究了通过AAA和Monte Carlo模拟计算的小骨关节的剂量学偏差。 AAA无法预测关节剂量随其宽度和束角的变化,这是由蒙特卡洛模拟所预测的。PACS编号:87.55.K-; 87.53.Bn; 87.53.-j

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