In vitro Assessment of Antimicrobial Efficacy of Alcoholic Extract of Achillea Millefolium in Comparison with Penicillin Derivatives

摘要

Achillea millefolium (Yarrow) has been used as a spice and medicinal plant in many ancient cultures from olden times. Today, biochemical investigations have shown different bioactive components responsible to medicinal and therapeutic properties of yarrow, in particular antimicrobial effect of it. Aim of this study is in vitro assessment of potential of inhibitory function of alcoholic extract of Achillea. millefolium on some microorganisms and comparison antimicrobial activity of yarrow with some antibiotics from penicillin family. The plants were used in this investigation, collected from Urmia region. The alcoholic extract of aerial parts of Achillea millefolium has been tested for antimicrobial activity in a disk diffusion assay. Also, microorganisms were used in this examination were divided in 2 categories: Control (Staphylococcus aureus, Salmonella enteritidis, Escherichia coli) and clinical isolated microorganisms (Staphylococcus aureus, Sterptococos Pneumoniae, Escherichia coli, Klebsiella pneumoniae, Pseudomonas aeruginosa, Enterobacter aerogenes, Proteus mirabilis) and 2 fungi (Aspergillus niger and Candida albicans). According to results of this study, the most sensitive organism to extract of yarrow was Staphylococcus aureus (pin vivo and clinically.