Targeting of phosphatidylserine by monoclonal antibodies enhances activity of immune checkpoint inhibitors in breast tumors

Jian Gong; Van Nguyen; Shen Yin; Rich Archer; Emely Nguyen; Jeff Hutchins; Bruce Freimark

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Targeting of phosphatidylserine by monoclonal antibodies enhances activity of immune checkpoint inhibitors in breast tumors

机译：单克隆抗体靶向磷脂酰丝氨酸可增强乳腺肿瘤中免疫检查点抑制剂的活性

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《Journal for ImmunoTherapy of Cancer》 |2014年第s3期|共页
作者
Jian Gong; Van Nguyen; Shen Yin; Rich Archer; Emely Nguyen; Jeff Hutchins; Bruce Freimark;
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中图分类肿瘤学;
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1. Targeting of phosphatidylserine by monoclonal antibodies enhances activity of immune checkpoint inhibitors in breast tumors [J] . Jian Gong, Van Nguyen, Shen Yin, Journal for ImmunoTherapy of Cancer . 2014,第S3期

机译：单克隆抗体靶向磷脂酰丝氨酸可增强乳腺肿瘤中免疫检查点抑制剂的活性
2. Antibody-mediated blockade of phosphatidylserine enhances the anti-tumor activity of targeted therapy and immune checkpoint inhibitors by affecting myeloid and lymphocyte populations in the tumor microenvironment [J] . Adam Yopp, Nikoletta Kallinteris, Xianming Huang, Journal for ImmunoTherapy of Cancer . 2014,第S3期

机译：抗体介导的磷脂酰丝氨酸阻断作用通过影响肿瘤微环境中的髓样和淋巴细胞群体，增强了靶向治疗和免疫检查点抑制剂的抗肿瘤活性
3. Phosphatidylserine-targeting antibodies augment the anti-tumorigenic activity of anti-PD-1 therapy by enhancing immune activation and downregulating pro-oncogenic factors induced by T-cell checkpoint inhibition in murine triple-negative breast cancers [J] . Michael J. Gray, Jian Gong, Michaela M. S. Hatch, Breast Cancer Research . 2016,第1期

机译：磷脂酰综合抗体通过增强免疫激活和下调由T细胞检查点抑制在鼠三重阴性乳腺癌中诱导的促致致因因子来增加抗致致瘤活性的抗致致荷致致致致致致致瘤活性。
4. Generation of Agonist and Antagonist Human Monoclonal Antibodies Against an Immune Checkpoint Target from the H2L2 Mouse [C] . Joshua K, Lowitz, John S. Kenney, Protein Engineering Summit. . 2018

机译：从H 2L 2小鼠产生激动剂和拮抗剂人单克隆抗体对抗免疫检查点靶标
5. Understanding How Adrenergic Stress Signaling Impacts the Anti-Tumor Immune Response and the Efficacy of Checkpoint Inhibitors in Murine Tumor Models [D] . Bucsek, Mark Joseph. 2019

机译：了解肾上腺素能应激信号如何影响抗肿瘤免疫应答以及检查点抑制剂在鼠肿瘤模型中的疗效
6. Targeting of phosphatidylserine by monoclonal antibodies enhances activity of immune checkpoint inhibitors in breast tumors [O] . Jian Gong, Van Nguyen, Shen Yin, 2014

机译：单克隆抗体靶向磷脂酰丝氨酸可增强乳腺肿瘤中免疫检查点抑制剂的活性
7. Targeting of phosphatidylserine by monoclonal antibodies enhances activity of immune checkpoint inhibitors in breast tumors [O] . Jian Gong, Van Nguyen, Shen Yin, 2014

机译：单克隆抗体靶向磷脂酰丝氨酸可增强乳腺肿瘤中免疫检查点抑制剂的活性
8. Radiolabeling and biotinylation of internalizing monoclonal antibody chimeric BR96: Potential use of extracorporeal immunoadsorption with enhanced tumor radioactivity retention of Iodine, Indium and Rhenium [R] . Chen, J. 1997

机译：内化单克隆抗体嵌合BR96的放射性标记和生物素化：体外免疫吸附的潜在用途，增强了碘，铟和铼的肿瘤放射性保留

Targeting of phosphatidylserine by monoclonal antibodies enhances activity of immune checkpoint inhibitors in breast tumors

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