Enhanced efficacy of ALT-803, an IL-15-based superagonist complex, in combination with immune checkpoint inhibitors in an orthotopic muscle invasive bladder tumor model in mice

Wenxin Xu; Karen Kage; Warren D Marcus; Robby Newman; Sarah Alter; Peter R Rhode; Hing C Wong

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Enhanced efficacy of ALT-803, an IL-15-based superagonist complex, in combination with immune checkpoint inhibitors in an orthotopic muscle invasive bladder tumor model in mice

机译：ALT-803（一种基于IL-15的超激动剂复合物）与免疫检查点抑制剂联合在小鼠原位肌肉浸润性膀胱肿瘤模型中的增强功效

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《Journal for ImmunoTherapy of Cancer》 |2015年第s2期|共页
作者
Wenxin Xu; Karen Kage; Warren D Marcus; Robby Newman; Sarah Alter; Peter R Rhode; Hing C Wong;
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中图分类肿瘤学;
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1. Enhanced efficacy of IL-15-based ALT-803 superagonist complex in combination with immune checkpoint inhibitors in hematologic and metastatic mouse tumor models [J] . Wenxin Xu, Warren D Marcus, Peter R Rhode, Journal for ImmunoTherapy of Cancer . 2014,第S3期

机译：基于IL-15的ALT-803超激动剂复合物与免疫检查点抑制剂联合在血液和转移性小鼠肿瘤模型中的功效增强
2. Effectiveness of two different dose administration regimens of an IL-15 superagonist complex (ALT-803) in an orthotopic bladder cancer mouse model [J] . Hideki Furuya, Owen T. M. Chan, Ian Pagano, Journal of Translational Medicine . 2019,第1期

机译：两种不同剂量给药方案在原位膀胱癌小鼠模型中的两种不同剂量给药方案的效果
3. Combination therapy of an IL-15 superagonist complex, ALT-803, and a tumor targeting monoclonal antibody promotes direct antitumor activity and protective vaccinal effect in a syngenic mouse melanoma model [J] . Xiaoyue Chen, Bai Liu, Kaiping Han, Journal for ImmunoTherapy of Cancer . 2015,第S2期

机译：IL-15超激动剂复合物ALT-803和肿瘤靶向单克隆抗体的联合治疗可促进同基因小鼠黑素瘤模型的直接抗肿瘤活性和保护性疫苗作用
4. Combination of angiogenesis inhibitors increases the anti-tumor efficacy of photodynamic therapy in a human bladder tumor xenograft model [C] . Ramaswamy Bhuvaneswari, Yik Yuen Gan, Patricia SP Thong, World congress of the International Photodynamic Association . 2009

机译：血管生成抑制剂的组合增加了光动力疗法在人膀胱肿瘤异种移植模型中的抗肿瘤功效
5. Understanding How Adrenergic Stress Signaling Impacts the Anti-Tumor Immune Response and the Efficacy of Checkpoint Inhibitors in Murine Tumor Models [D] . Bucsek, Mark Joseph. 2019

机译：了解肾上腺素能应激信号如何影响抗肿瘤免疫应答以及检查点抑制剂在鼠肿瘤模型中的疗效
6. Enhanced efficacy of ALT-803 an IL-15-based superagonist complex in combination with immune checkpoint inhibitors in an orthotopic muscle invasive bladder tumor model in mice [O] . Wenxin Xu, Karen Kage, Warren D Marcus, 2015

机译：ALT-803（一种基于IL-15的超激动剂复合物）与免疫检查点抑制剂组合在小鼠原位肌肉浸润性膀胱肿瘤模型中的增强功效
7. Enhanced efficacy of ALT-803, an IL-15-based superagonist complex, in combination with immune checkpoint inhibitors in an orthotopic muscle invasive bladder tumor model in mice [O] . Wenxin Xu, Karen Kage, Warren D Marcus, 2015

机译：ALT-803（一种基于IL-15的超激动剂复合物）与免疫检查点抑制剂组合在小鼠原位肌肉浸润性膀胱肿瘤模型中的增强功效
8. Contrast-enhanced computed tomography of the primary tumor in muscle invasive carcinoma of the urinary bladder [R] . Sager, E. M. 1991

机译：对比增强的计算机断层扫描的原发性肿瘤在膀胱肌肉浸润癌

Enhanced efficacy of ALT-803, an IL-15-based superagonist complex, in combination with immune checkpoint inhibitors in an orthotopic muscle invasive bladder tumor model in mice

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