Facile construction of substituted pyrimido[4,5-d]pyrimidones by transformation of enaminouracil

Wafaa S. Hamama; Mohamed A. Ismail; Hanaa A. Al-Saman; Hanafi H. Zoorob

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Facile construction of substituted pyrimido[4,5-d]pyrimidones by transformation of enaminouracil

机译：通过烯胺尿嘧啶的转化轻松构建取代的嘧啶并[4,5-d]嘧啶酮

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The reaction of 6-amino-1,3-dimethylpyrimidine-2,4(1H,3H)-dione (1) as a binucleophile with primary aromatic or heterocyclic amines and formaldehyde or aromatic (heterocyclic) aldehydes in a molar ratio (1:1:2) gave the pyrimido[4,5-d]pyrimidin-2,4-dione

机译：6-氨基-1,3-二甲基嘧啶-2,4（1H，3H）-二酮（1）作为双亲核试剂与伯芳族或杂环胺和甲醛或芳族（杂环）醛以摩尔比（1： 1：2）得到嘧啶基[4,5-d]嘧啶-2,4-二酮

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《Journal of Advanced Research》 |2013年第2期|共7页
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Wafaa S. Hamama; Mohamed A. Ismail; Hanaa A. Al-Saman; Hanafi H. Zoorob;
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中图分类生物科学;
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入库时间 2022-08-18 15:58:12

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Facile construction of substituted pyrimido[4,5-d]pyrimidones by transformation of enaminouracil

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