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Meningitis due to Moraxella nonliquefaciens in a paediatric patient: a case report and review of the literature

机译:小儿莫拉氏菌引起的脑膜炎:一例病例报告并文献复习

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Moraxella nonliquefaciens is an unusual organism to be isolated from cerebral spinal fluid (CSF) and there exists only one case report of M. nonliquefaciens meningitis from a neonate. Moraxella species normally exist as part of the human upper respiratory tract flora and rarely cause invasive human disease. There are only a handful of case reports implicating the organism as a cause of endocarditis, bacteraemia, septic arthritis and endophthalmitis. Identification to the species level based on routine laboratory techniques has been challenging, with final identification often made through 16S rRNA sequencing. With the use of a newer diagnostic tool, matrix-assisted laser desorption ionization-time of flight (MALDI-TOF) MS, we were able to rapidly identify the organism and initiate appropriate treatment.
机译:非液化莫拉氏菌是一种从脑脊髓液(CSF)中分离出来的不寻常生物,仅存在一例新生儿非液化莫拉氏菌脑膜炎的病例报道。莫拉氏菌通常作为人类上呼吸道菌群的一部分而存在,很少引起人类侵袭性疾病。仅有少数病例报道该生物体是心内膜炎,菌血症,败血性关节炎和眼内炎的病因。根据常规实验室技术进行物种鉴定一直是一项挑战,最终鉴定通常通过16S rRNA测序进行。使用更新的诊断工具,基质辅助激光解吸电离飞行时间(MALDI-TOF)MS,我们能够快速识别出该生物并开始适当的治疗。

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