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首页> 外文期刊>Developmental Immunology: Journal of Immunology Research >Enteropathic Spondyloarthritis: From Diagnosis to Treatment
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Enteropathic Spondyloarthritis: From Diagnosis to Treatment

机译:肠病性脊柱关节炎:从诊断到治疗

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摘要

Enteropathic arthritis (EA) is a spondyloarthritis (SpA) which occurs in patients with inflammatory bowel diseases (IBDs) and other gastrointestinal diseases. Diagnosis is generally established on the medical history and physical examination. It was, generally, made according to the European Spondyloarthropathy Study Group (ESSG) criteria. Rheumatic manifestations are the most frequent extraintestinal findings of IBD with a prevalence between 17% and 39%, and IBD is associated, less frequently, with other rheumatic disease such as rheumatoid arthritis, Sjogren syndrome, Takayasu arteritis, and fibromyalgia. Although the pathogenesis of EA has not been plainly clarified, the most popular theory supposes that joint inflammation occurs in genetically predisposed subjects with bacterial gut infections, provided an important evidence for a possible relationship between inflammation of the gut mucosa and arthritis. The management of patients with EA requires an active cooperation between the gastroenterologist and rheumatologist.
机译:肠病性关节炎(EA)是一种脊柱关节炎(SpA),发生在患有炎症性肠病(IBDs)和其他胃肠道疾病的患者中。诊断通常根据病史和体格检查确定。通常,它是根据欧洲脊椎关节病研究小组(ESSG)的标准制成的。风湿病是IBD最常见的肠外发现,患病率在17%至39%之间,IBD与其他风湿性疾病如类风湿性关节炎,Sjogren综合征,Takayasu动脉炎和纤维肌痛的相关性较低。尽管尚未明确弄清EA的发病机理,但最流行的理论认为关节发炎发生在遗传易感细菌性肠感染的受试者中,为肠粘膜发炎与关节炎之间的可能关系提供了重要证据。 EA患者的治疗需要胃肠病学家和风湿病学家之间的积极合作。

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