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首页> 外文期刊>Developmental Immunology: Journal of Immunology Research >Pseudo Alopecia Areata Caused by Skull-caps with Metal Pin Fasteners used by Orthodox Jews in Israel
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Pseudo Alopecia Areata Caused by Skull-caps with Metal Pin Fasteners used by Orthodox Jews in Israel

机译:以色列正统犹太人使用带有金属别针紧固件的骷髅帽造成的假性脱发

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摘要

Background: Alopecia Areata (AA) is a disease characterized by hair loss that is widely believed to be autoimmune in origin. Thus treatment is generally aimed in this direction using immune inhibitors such as steroids and PUVA.Objective: To describe a variant of AA, Pseudo Alopecia Areata, caused by a particular cupola pin holder (tic-tac) and to offer a non-pharmacological treatment option (NPT).Methods: A prospective open label study in 37 Jewish religious patients (34 males, 3 females, mean 35 ± 2 years), previously diagnosed and treated for scalp AA were randomly referred to one of the three NPT intervention methods: small cupola held by two pins, large cupola held by one pin and similar cupola held by a different pin.Results: Three of the ten patients (33.3%) from the first group developed secondary AA from the additional pin. No changes were seen in the second group. Ten of the seventeen patients (58.8%) from the third group achieved immediate improvement subsequent to replacing the original pin with a new one on a larger cupola.Conclusions: Conservative pharmacological treatment failed to repair the lesions. The addition of a second pin caused an additional lesion. In contrast, replacing the cupola with a larger one and the original pin-fastener with a different type, successfully reduced the lesions.
机译:背景:脱发症(AA)是一种以脱发为特征的疾病,被普遍认为是自身免疫性疾病。因此,通常使用类固醇和PUVA等免疫抑制剂来朝这一方向进行治疗。目的:描述由特定冲天针固定器(tic-tac)引起的AA变种Pseudo Alopecia Areata,并提供非药物治疗方法:一项对37位犹太宗教患者(前瞻性,开放性研究)进行的前瞻性开放标签研究(先前为头皮AA的诊断和治疗)(37位男性,3位女性,平均35±2岁)被随机分配为以下三种NPT干预方法之一:小冲天炉由两个销钉夹持,大冲天炉由一个销钉夹持,而类似冲天炉由另一个销钉夹持。结果:第一组的十名患者中有三名(33.3%)从另一支销钉发展为继发性AA。在第二组中没有看到变化。第三组的17例患者中有10例(58.8%)在较大的穹顶上用新的针替换了原来的针后即刻得到了改善。结论:保守的药物治疗未能修复病变。添加第二个销钉会导致其他病变。相比之下,用较大的圆屋顶代替圆屋顶,而用不同类型的圆头紧固件则成功地减少了病变。

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