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首页> 外文期刊>Der Pharma Chemica: journal for medicinal chemistry, pharmaceutical chemistry and computational chemistry >Synthesis and Antibacterial Activity of 2-{2-[(4-`chlorophenyl)sulfanyl]ethoxy}-3-methoxy-5-[6-(3,4,5-trimethoxyphenyl)-3- pyridazinyl]benzonitrile
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Synthesis and Antibacterial Activity of 2-{2-[(4-`chlorophenyl)sulfanyl]ethoxy}-3-methoxy-5-[6-(3,4,5-trimethoxyphenyl)-3- pyridazinyl]benzonitrile

机译:2- {2-[(4-氯苯基)硫烷基]乙氧基} -3-甲氧基-5- [6-(3,4,5-三甲氧基苯基)-3-哒嗪基]苄腈的合成及抑菌活性

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摘要

The present paper describes the synthesis of the title compound, which is a hybrid scaffold of our earlier reported work on 2,5-diaryltetrahydrofuran, utilizing an inexpensive commercially available vanillin as starting material, in over all eight steps. The newly synthesized title compound, displayed excellent to moderate activity towards the bacterial strains tested.
机译:本文介绍了标题化合物的合成,该化合物是我们较早前报道的有关2,5-二芳基四氢呋喃的杂交支架,在所有八个步骤中均使用廉价的市售香兰素作为起始原料。新合成的标题化合物对测试的细菌菌株显示出极好的至中等的活性。

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