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Facial actinic lichen nitidus successfully treated with hydroxychloroquin: a case report

机译:羟基氯喹成功治疗面部光化性地衣针

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Introduction?: Lichen nitidus ?is an unusual condition with chronic evolution. It arises as multiple tiny, shiny papules with a flat surface. Many clinical variants have been reported. We describe a new case of facial actinic lichen nitidus. Our patient responded rapidly to corticosteroids and hydroxychloroquine.Case report: A 23-year-old woman with photodistributed eruptions recurring during the summer with improvement during the winter presented to our institution. Clinical exam revealed pinhead sized flat and flesh-colored papules on her face. Koebner phenomenon was not observed. Palms, soles, nails, and mucosa were normal. Histologic examination of a cutaneous biopsy showed a well circumscribed lymphohistiocytic infiltrate in the papillary dermis in a “claw clutching a ball” pattern suggestive of lichen nitidus. The diagnosis of actinic lichen nitidus was made. Treatment included photoprotection, topical corticosteroids once daily for 6 weeks, and hydroxychloroquine for 6 months. ?Remission of lesions was obtained after 4 weeks.Conclusion: Actinic lichen nitidus is rare. The true prevalence of this disease and the effectiveness of its various therapies is difficult to evaluate because it is usually asymptomatic and resolves without squelae.
机译:简介:地衣的针叶病是一种具有慢性演变的异常情况。它以表面平坦的多个细小,闪亮的丘疹出现。已经报道了许多临床变体。我们描述了一个新的面部光化性地衣nitidus病例。病人对皮质类固醇和羟氯喹的反应迅速。病例报告:一名23岁的女性在夏季反复发作光分布性爆发,并向我们机构介绍了冬季的改善情况。临床检查发现她的脸上长有针头大小的扁平且肉色丘疹。没有观察到Koebner现象。手掌,脚底,指甲和粘膜正常。皮肤活检的组织学检查显示,乳头状真皮中有良好的淋巴组织细胞浸润,呈“抓球”状,提示有地衣针状。诊断为光化性地衣。治疗包括光保护,每天一次局部皮质类固醇激素治疗6周,以及羟氯喹治疗6个月。 4周后皮损得到缓解。结论:光化性地衣针很少见。这种疾病的真正患病率及其各种疗法的有效性很难评估,因为它通常是无症状的且无后遗症即可治愈。

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