Evaluation of anthelmintic activity of hydro-alcoholic extract of Ailanthus excelsa stem bark

摘要

Main aim of present study is to evaluate anthelmintic potential of hydro - alcoholic extract of Ailanthus excelsa stem bark. During the study period, concentration (100mg/5ml, 250mg/5ml, 500mg/5ml) of hydro - alcoholic extract were used for determining the paralysis time and death time of earthworms (Pheretima posthuma). At the concentration of 500mg/5ml time required for paralysis (60±0.81 min) and death (73±2.44 min) is minimum. The time required for paralysis and death of earthworms at the concentration of 250 mg/5ml is (229±1.29 min), (249±2.70 min) respectively and at the concentration of 100 mg/5ml time required for paralysis and death of earthworms was (499±1.29 min), (539.5±1.30 min).From the study it was observed that at the higher concentration of the extract time required for causing paralysis (60±0.81 min) and death of earthworms (73±2.44 min) is less in comparison to the time required for causing paralysis (120.5±1.29 min) and death (148±2.36 min) of earthworms by the standard drug ( Piperazine citrate).