Reactive angioendotheliomatosis associated with cyroglobulinemia in a marathon runner

摘要

We report a case of a 65-year-old marathon runner who presented with painful plaques, which were worse in cold weather and? progressed to ulceration. A punch biopsy revealed vascular endothelial hyperplasia and an appearance consistent with reactive angioendotheliomatosis (RAE), a rare, but benign disorder of the skin.? Subsequent? investigations? resulted? in? the? diagnosis? of? type? I cryoglobulinemia; the? lesions? resolved? completely? following? treatment? of the underlying disorder with lenalidomide.