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Transcriptome analyses of sex differential gene expression in brains of rare minnow ( Gobiocypris rarus) and effects of tributyltin exposure

机译:稀有min鱼( Gobiocypris rarus )大脑性别差异基因表达的转录组分析及三丁基锡暴露的影响

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RNA-sequencing was used to identify sex-biased gene expression in brains of rare minnow ( Gobiocypris rarus ) by comparing transcriptomic profiles between females and males. Furthermore, transcriptomic responses to 10?ng/L tributyltin (TBT) in both male and female brains were also investigated to understand whether TBT affects the identified sex-biased genes. Differentially expressed genes (DEGs) were identified using the IDEG6 web tool. In this article, we presented male- and female-biased DEGs, and up-regulated and down-regulated DEGs after TBT exposure. The raw reads data supporting the present analyses has been deposited in NCBI Sequence Read Archive (SRA, http://www.ncbi.nlm.nih.gov/Traces/sra ) with accession number PRJNA376634. The data presented in this article are related to the research article entitled “Transcriptomic analyses of sexual dimorphism of rare minnow ( G. rarus ) brains and effects of tributyltin exposure” (doi: 10.1016/j.ecoenv.2018.02.049).
机译:通过比较雌性和雄性之间的转录组谱,RNA测序被用于鉴定稀有min鱼(Gobiocypris rarus)大脑中的性别偏向基因表达。此外,还研究了男性和女性大脑中对10μng/ L三丁基锡(TBT)的转录反应,以了解TBT是否影响已鉴定的性别偏向基因。使用IDEG6网络工具鉴定了差异表达的基因(DEG)。在本文中,我们介绍了男性和女性偏爱的DEG,以及暴露于TBT之后的DEG上调和下调。支持本分析的原始阅读数据已保存在NCBI Sequence Read Archive(SRA,http://www.ncbi.nlm.nih.gov/Traces/sra)中,登录号为PRJNA376634。本文中提供的数据与题为“稀有min鱼(G. rarus)脑性二态性的转录组学分析和三丁基锡暴露的影响”的研究文章有关(doi:10.1016 / j.ecoenv.2018.02.049)。

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