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National burden of the pharmaceutical cost of wet compresses and its cost predictors: nationwide cross-sectional study in Japan

机译:湿敷物药品成本的国家负担及其成本预测因素:日本的全国性横断面研究

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Background Although a high number of wet compresses are prescribed daily in medical institutions in Japan, our understanding of the national burden of the cost of wet compresses and the details regarding their prescription is far from complete. We investigated the national burden of the annual pharmaceutical cost of wet compresses prescribed in Japan and estimated the predictors of this cost using nationwide health insurance claims data. Methods We extracted the records on wet compress products from summary table files obtained from the second version of the “NDB Open Data Japan” website and calculated the annual pharmaceutical cost of wet compresses by patients’ 5-year age group, sex, and prefecture. We also conducted an ecological study treating each prefecture as an individual unit and multiple linear regression analyses using the age-standardized cost of wet compresses per resident as a dependent variable. Results The annual pharmaceutical cost of wet compresses prescribed in Japan in fiscal year 2015 was 149.0 billion Japanese yen (1.18 billion euros; 1.33 billion USD). Multiple linear regression analyses showed that the number of orthopedists and rehabilitation physicians per 100,000 residents were significantly positively associated with the annual pharmaceutical cost of wet compresses per resident ( P ?=?0.042 and P ?=?0.008, respectively). Conclusions The annual pharmaceutical cost of wet compresses prescribed in Japan has a considerable impact on the nation’s limited healthcare resources. The number of orthopedists and rehabilitation physicians per 100,000 residents may be independent predictors of the wet compress cost in Japan.
机译:背景技术尽管在日本的医疗机构中每天都会开出大量的湿敷布,但我们对湿敷布成本的国家负担及其处方细节的了解还远远不够。我们调查了日本规定的湿敷年药品成本的国家负担,并使用全国健康保险理赔数据估算了该成本的预测因素。方法我们从第二版“ NDB日本公开数据”网站获得的摘要表文件中提取湿敷产品的记录,并按患者的5岁年龄段,性别和县计算湿敷产品的年度药品成本。我们还进行了生态研究,将每个县作为一个独立的单位进行处理,并使用年龄标准化的每个居民湿敷物的成本作为因变量,进行了多个线性回归分析。结果2015财年,日本规定的湿敷片年度药品成本为1490亿日元(11.8亿欧元; 13.3亿美元)。多元线性回归分析表明,每10万名居民中骨科医生和康复医生的人数与每名居民每年湿敷的药物成本显着正相关(分别为P = 0.042和P = 0.008)。结论日本规定的湿敷物的年度药品成本对日本有限的医疗资源具有相当大的影响。每十万居民中骨科医生和康复医生的人数可能是日本湿敷成本的独立预测指标。

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