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Perioperative Care of Patients With Liver Cirrhosis: A Review

机译:肝硬化患者的围手术期护理

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The incidence of cirrhosis is rising, and identification of these patients prior to undergoing any surgical procedure is crucial. The preoperative risk stratification using validated scores, such as Child-Turcotte-Pugh (CTP) and Model for End-Stage Liver Disease, perioperative optimization of hemodynamics and metabolic derangements, and postoperative monitoring to minimize the risk of hepatic decompensation and complications are essential components of medical management. The advanced stage of cirrhosis, emergency surgery, open surgeries, old age, and coexistence of medical comorbidities are main factors influencing the clinical outcome of these patients. Perioperative management of patients with cirrhosis warrants special attention to nutritional status, fluid and electrolyte balance, control of ascites, excluding preexisting infections, correction of coagulopathy and thrombocytopenia, and avoidance of nephrotoxic and hepatotoxic medications. Transjugular intrahepatic portosystemic shunt may improve the CTP class, and semielective surgeries may be feasible. Emergency surgery, whenever possible, should be avoided.
机译:肝硬化的发生率正在上升,因此在进行任何外科手术之前识别这些患者至关重要。使用经过验证的评分进行术前风险分层,例如Child-Turcotte-Pugh(CTP)和终末期肝病模型,围手术期血流动力学和代谢紊乱的优化以及术后监测以最大程度地减少肝代偿失调和并发症的风险,是至关重要的组成部分医疗管理。肝硬化的晚期,急诊手术,开放手术,老年以及合并症是这些患者临床结局的主要因素。肝硬化患者的围手术期管理应特别注意营养状况,体液和电解质平衡,控制腹水(不包括既往感染),纠正凝血病和血小板减少症以及避免使用肾毒性和肝毒性药物。经颈静脉肝内门体分流术可改善CTP等级,半电外科手术是可行的。应尽可能避免进行急诊手术。

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