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Integrating clinicians, knowledge and data: expert-based cooperative analysis in healthcare decision support

机译:整合临床医生,知识和数据:医疗决策支持中基于专家的合作分析

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Background Decision support in health systems is a highly difficult task, due to the inherent complexity of the process and structures involved. Method This paper introduces a new hybrid methodology Expert-based Cooperative Analysis (EbCA), which incorporates explicit prior expert knowledge in data analysis methods, and elicits implicit or tacit expert knowledge (IK) to improve decision support in healthcare systems. EbCA has been applied to two different case studies, showing its usability and versatility: 1) Bench-marking of small mental health areas based on technical efficiency estimated by EbCA-Data Envelopment Analysis (EbCA-DEA), and 2) Case-mix of schizophrenia based on functional dependency using Clustering Based on Rules (ClBR). In both cases comparisons towards classical procedures using qualitative explicit prior knowledge were made. Bayesian predictive validity measures were used for comparison with expert panels results. Overall agreement was tested by Intraclass Correlation Coefficient in case "1" and kappa in both cases. Results EbCA is a new methodology composed by 6 steps:. 1) Data collection and data preparation; 2) acquisition of "Prior Expert Knowledge" (PEK) and design of the "Prior Knowledge Base" (PKB); 3) PKB-guided analysis; 4) support-interpretation tools to evaluate results and detect inconsistencies (here Implicit Knowledg -IK- might be elicited); 5) incorporation of elicited IK in PKB and repeat till a satisfactory solution; 6) post-processing results for decision support. EbCA has been useful for incorporating PEK in two different analysis methods (DEA and Clustering), applied respectively to assess technical efficiency of small mental health areas and for case-mix of schizophrenia based on functional dependency. Differences in results obtained with classical approaches were mainly related to the IK which could be elicited by using EbCA and had major implications for the decision making in both cases. Discussion This paper presents EbCA and shows the convenience of completing classical data analysis with PEK as a mean to extract relevant knowledge in complex health domains. One of the major benefits of EbCA is iterative elicitation of IK.. Both explicit and tacit or implicit expert knowledge are critical to guide the scientific analysis of very complex decisional problems as those found in health system research.
机译:背景技术由于所涉及的过程和结构的内在复杂性,卫生系统中的决策支持是一项非常困难的任务。方法本文介绍了一种新的混合方法,即基于专家的合作分析(EbCA),它在数据分析方法中结合了明确的先验专家知识,并通过隐性或隐性专家知识(IK)来改善医疗保健系统的决策支持。 EbCA已应用于两个不同的案例研究,显示了其可用性和多功能性:1)基于EbCA数据包络分析(EbCA-DEA)估算的技术效率对小型精神卫生领域进行基准测试,以及2)使用基于规则的聚类(ClBR)基于功能依赖性的精神分裂症。在这两种情况下,均使用定性的先验知识对经典程序进行了比较。贝叶斯预测效度度量用于与专家组结果进行比较。总体一致性通过案例“ 1”中的类内相关系数和kappa进行了测试。结果EbCA是一种由6个步骤组成的新方法: 1)数据收集与准备; 2)获得“专家知识”(PEK)和“知识库”(PKB)的设计; 3)PKB指导的分析; 4)支持解释工具,用于评估结果和检测不一致之处(此处可能会得出隐式知识-IK-); 5)将引发的IK合并到PKB中,并重复进行直至获得满意的解决方案; 6)对后处理结果进行决策支持。 EbCA有助于将PEK纳入两种不同的分析方法(DEA和聚类),分别用于评估小型精神卫生领域的技术效率和基于功能依赖性的精神分裂症病例组合。用经典方法获得的结果差异主要与IK有关,而IK可以通过使用EbCA引起,这对两种情况下的决策都具有重要意义。讨论本文介绍了EbCA,并显示了使用PEK作为提取复杂卫生领域中相关知识的手段来完成经典数据分析的便利性。 EbCA的主要优点之一是IK的迭代启发。显性和默认或隐式专家知识对于指导对非常复杂的决策问题(如卫生系统研究中发现的问题)的科学分析都至关重要。

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